Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.37 |
| ▸ | MMP12 | P39900 | 7/20 | 0.37 |
| ▸ | MMP7 | P09237 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060514 | 1.00 | ADAM17 (0.37) | ADAM17MMP12MMP7MMP3CHRM4 | |
| SCHEMBL4060509 | 1.00 | ADAM17 (0.37) | ADAM17MMP12MMP7MMP3CHRM4 | |
| SCHEMBL4050516 | 0.85 | AR (0.46) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4050512 | 0.85 | AR (0.46) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4056371 | 0.83 | ADAM17 (0.45) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4056379 | 0.83 | ADAM17 (0.45) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4054238 | 0.79 | MMP3 (0.59) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4054243 | 0.79 | MMP3 (0.59) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4057743 | 0.79 | MMP12 (0.61) | ADAM17MMP12MMP7MMP3MMP2 | |
| SCHEMBL4057747 | 0.79 | MMP12 (0.61) | ADAM17MMP12MMP7MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |