Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112741 | 0.89 | LMNA (0.59) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL26064326 | 0.89 | MAOA (0.46) | TSHRKMT2ACYP1A2HDAC6PMP22 | |
| SCHEMBL288952 | 0.88 | MAOA (0.48) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL11896840 | 0.87 | LMNA (0.56) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL1741769 | 0.87 | LMNA (0.56) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL5085152 | 0.85 | LMNA (0.59) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL31271806 | 0.84 | MAOA (0.54) | KMT2ACYP1A2HDAC6MEN1ALOX15 | |
| SCHEMBL2461935 | 0.84 | LMNA (0.53) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL7389117 | 0.84 | LMNA (0.53) | LMNASLC22A6TSHRTHRBBLM | |
| SCHEMBL2468753 | 0.84 | LMNA (0.53) | LMNASLC22A6TSHRTHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-A2 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2003-09-03 | — | — | EP | claimed |
| WO-2002042256-A2 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2002-05-30 | — | — | WO | claimed |
| EP-2049476-A1 | PROCESS FOR THE PREPARATION OF LEVETIRACETAM | ZaCh System S.p.A. (IT) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012268-A1 | PROCESS FOR THE PREPARATION OF LEVETIRACETAM | ZACH SYSTEM S.P.A. (IT) | 2008-01-31 | — | — | WO | disclosed |