Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250162 | 0.95 | TRIM24 (0.46) | L3MBTL1TDP1TRIM24TRIM33NPC1 | |
| SCHEMBL26143989 | 0.88 | TRIM24 (0.48) | L3MBTL1TDP1TRIM24TRIM33NPC1 | |
| SCHEMBL23505874 | 0.87 | TDP1 (0.45) | L3MBTL1TDP1TRIM24TRIM33KCNH2 | |
| SCHEMBL9502638 | 0.81 | KDM4E (0.44) | TRIM24TRIM33KMT2AKDM4EMEN1 | |
| SCHEMBL9768756 | 0.80 | TRIM24 (0.52) | L3MBTL1TDP1TRIM24TRIM33NPC1 | |
| SCHEMBL2903484 | 0.78 | L3MBTL1 (0.39) | L3MBTL1TDP1NPC1RAB9AKMT2A | |
| SCHEMBL31190150 | 0.77 | TDP1 (0.49) | L3MBTL1TDP1KCNH2TRPV1PPARA | |
| SCHEMBL28876834 | 0.76 | TDP1 (0.47) | L3MBTL1TDP1KCNH2TRPV1PPARA | |
| SCHEMBL28219671 | 0.76 | TDP1 (0.47) | L3MBTL1TDP1KCNH2TRPV1PPARA | |
| SCHEMBL461554 | 0.75 | TDP1 (0.50) | L3MBTL1TDP1KCNH2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528256-B2 | Process for the preparation of nicotinaldehydes | MERCK PATENT GMBH (DE) | 2009-05-05 | — | — | US | disclosed |
| US-20060199965-A1 | Process for the preparation of nicotinaldehydes | MERCK PATENT GMBH (DE) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199965-A1 | Process for the preparation of nicotinaldehydes | NAMPT, NAPRT, NNMT | L3MBTL1 4878/4885TDP1 3319/4885TRIM24 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.