Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17595558 | 0.82 | TRIM24 (0.48) | KDM4ETRIM24TRIM33HPGDMEN1 | |
| SCHEMBL4564967 | 0.81 | L3MBTL1 (0.45) | KDM4ETRIM24TRIM33MEN1KMT2A | |
| SCHEMBL250162 | 0.79 | TRIM24 (0.46) | KDM4ETRIM24TRIM33HPGDMEN1 | |
| SCHEMBL13278055 | 0.76 | KDM4E (0.53) | KDM4EHCAR2DAGLAMAPTMEN1 | |
| SCHEMBL13277607 | 0.76 | KDM4E (0.53) | KDM4EHCAR2DAGLAMAPTMEN1 | |
| SCHEMBL13278076 | 0.76 | KDM4E (0.53) | KDM4EHCAR2DAGLAMAPTMEN1 | |
| SCHEMBL9142138 | 0.75 | SIGMAR1 (0.50) | SIGMAR1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL7091261 | 0.75 | SIGMAR1 (0.50) | SIGMAR1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL26143989 | 0.75 | TRIM24 (0.48) | KDM4ETRIM24TRIM33HPGDMEN1 | |
| SCHEMBL6000358 | 0.74 | ALDH1A1 (0.65) | SIGMAR1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |