SCHEMBL4565010

SCHEMBL4565010

Cc1ccc(NC(Cc2ccccc2)C(=O)CCl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSG P08311 3/20 0.50
CMA1 P23946 3/20 0.50
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MMP9 P14780 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
PSMB5 P28074 2/20 0.44
IDO1 P14902 1/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
TACR1 P25103 1/20 0.43
PPARG P37231 1/20 0.43
PSMB8 P28062 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2957410 1.00 CTSG (0.50) CTSGCMA1GAAMAPTMAPK1
SCHEMBL1023659 0.86 GAA (0.47) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL21373234 0.86 PPARG (0.49) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL21373232 0.86 PPARG (0.49) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL10692667 0.85 PPARG (0.55) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL7100965 0.85 PPARG (0.55) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL10690468 0.83 PPARG (0.51) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL10690483 0.83 PPARG (0.51) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL28085748 0.82 MAPK1 (0.49) GAAMAPTMAPK1NPSR1MMP9
SCHEMBL10690475 0.82 MMP9 (0.48) GAAMAPTMAPK1NPSR1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1552269-A2 FORMALDEHYDE-AMMONIUM SALT COMPLEXES FOR THE STABILIZATION OF BLOOD CELLS Coulter International Corp. (US) 2005-07-13 EP claimed
US-6913932-B2 Formaldehyde-ammonium salt complexes for the stabilization of blood cells BECKMAN COULTER, INC. (US) 2005-07-05 US claimed
WO-2004017895-A2 FORMALDEHYDE-AMMONIUM SALT COMPLEXES FOR THE STABILIZATION OF BLOOD CELLS COULTER INTERNATIONAL CORP. (US) 2004-03-04 WO claimed
US-20040038424-A1 Formaldehyde-ammonium salt complexes for the stabilization of blood cells BECKMAN COULTER, INC. 2004-02-26 US claimed
EP-3529371-A1 A FUNCTIONAL DETECTION ASSAY DEVOID OF ANTIBODIES FOR SEROTYPING OF BOTULINUM NEUROTOXINS Toxogen GmbH (DE) 2019-08-28 EP disclosed
WO-2018073370-A1 A FUNCTIONAL DETECTION ASSAY DEVOID OF ANTIBODIES FOR SEROTYPING OF BOTULINUM NEUROTOXINS TOXOGEN GMBH (DE) 2018-04-26 WO disclosed
US-20140308668-A1 Method of Determining Susceptibility of a Tumor Cell to a Chemotherapeutic Agent: Novel Use of Herpes SImplex Virus MEDICAL DIAGNOSTIC LABORATORIES L. L. C. 2014-10-16 US disclosed
US-8778331-B2 Method of determining susceptibility of a tumor cell to a chemotherapeutic agent: novel use of herpes simplex virus MEDICAL DIAGNOSTIC LABORATORIES, LLC (US) 2014-07-15 US disclosed
US-8309788-B2 Protease inhibitors in absorbent articles THE PROCTER AND GAMBLE COMPANY (US) 2012-11-13 US disclosed
US-8262634-B1 Absorbent article having barrier sheet against the migration of the skin care composition THE PROCTER & GAMBLE COMPANY (US) 2012-09-11 US disclosed
US-20090325146-A1 Method of determining susceptibility of a tumor cell to a chemotherapeutic agent: novel use of herpes MEDICAL DIAGNOSTIC LABORATORIES, LLC (US) 2009-12-31 US disclosed
EP-1178846-B1 ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION PROCTER & GAMBLE (US) 2009-09-02 EP disclosed
WO-1997037044-A1 NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI AND VACCINE COMPOSITIONS THEREOF ASTRA AKTIEBOLAG (SE) 1997-10-09 WO disclosed
EP-0787016-A1 SECRETORY LEUKOCYTE PROTEASE INHIBITOR AS AN INHIBITOR OF TRYPTASE Bayer Corporation (US) 1997-08-06 EP disclosed
WO-1997019098-A1 NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI FOR DIAGNOSTICS AND THERAPEUTICS ASTRA AKTIEBOLAG (SE) 1997-05-29 WO disclosed
US-5633227-A POLYPEPTIDE MILES, INC. (US) 1997-05-27 US disclosed
WO-1996040893-A1 NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI FOR DIAGNOSTICS AND THERAPEUTICS ASTRA AKTIEBOLAG (SE) 1996-12-19 WO disclosed
WO-1996033209-A1 PEPTIDYL DERIVATIVES AS INHIBITORS OF PRO-APOPTOTIC CYSTEINE PROTEINASES MERCK FROSST CANADA INC. (CA) 1996-10-24 WO disclosed
WO-1996008275-A1 SECRETORY LEUKOCYTE PROTEASE INHIBITOR AS AN INHIBITOR OF TRYPTASE BAYER CORPORATION (US) 1996-03-21 WO disclosed
US-5273886-A Quantitatively methylating isoaspartyl residues in polypeptide fragments in a mixture of labeled S-adenosyl L-methionine in the presence of an L-isoaspartyl methyltransferase THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-12-28 US disclosed