Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 10/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 10/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 10/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565016 | 0.81 | SLC6A3 (0.49) | SLC6A3DRD1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11794700 | 0.74 | SLC6A4 (0.52) | SLC6A3DRD1SLC6A4 | |
| SCHEMBL4319951 | 0.71 | CYP3A4 (0.46) | SLC6A3SLC6A4 | |
| SCHEMBL4319946 | 0.71 | CHRNA7 (0.47) | SLC6A3SLC6A4 | |
| SCHEMBL10955829 | 0.70 | MAOA (0.50) | SLC6A3DRD1MAOAMAOBSLC6A4 | |
| Hydrochloric Acid SCHEMBL11795199 | 0.68 | DRD1 (0.53) | SLC6A3DRD1DRD5SLC6A4 | |
| SCHEMBL748775 | 0.67 | SLC6A4 (0.56) | SLC6A3DRD1SLC6A4 | |
| SCHEMBL10957422 | 0.66 | ACHE (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL11800672 | 0.66 | SLC6A4 (0.62) | SLC6A3DRD1SLC6A4 | |
| SCHEMBL16979269 | 0.65 | TRPV1 (0.54) | SLC6A3DRD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |