Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 6/20 | 0.64 |
| ▸ | AKT2 | P31751 | 4/20 | 0.64 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.64 |
| ▸ | PLCG2 | P16885 | 2/20 | 0.62 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082266 | 0.95 | AKT1 (0.70) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL749657 | 0.95 | AKT1 (0.70) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL4601441 | 0.88 | AKT1 (0.57) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL4199434 | 0.85 | AKT1 (0.85) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL11131399 | 0.85 | LPAR1 (0.56) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL5446081 | 0.85 | AKT1 (0.85) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL17416063 | 0.85 | AKT1 (0.85) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL6854208 | 0.80 | LPAR3 (0.76) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL30898875 | 0.80 | GPR55 (0.69) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL2732573 | 0.80 | LPAR3 (0.97) | LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052186-A1 | METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |