SCHEMBL749657

SCHEMBL749657

CCCCCOC[C@H](COP(=O)(O)OC1C(O)C(O)C(O)C(O)C1O)OCCCCC

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 6/20 0.70
AKT2 P31751 4/20 0.70
AKT3 Q9Y243 4/20 0.70
PIK3R1 P27986 3/20 0.70
PIK3CA P42336 3/20 0.70
PLCG2 P16885 2/20 0.65
GAB1 Q13480 1/20 0.65
LPAR1 Q92633 4/20 0.63
LPAR3 Q9UBY5 4/20 0.63
MAPK14 Q16539 2/20 0.57
LPAR2 Q9HBW0 1/20 0.56
GPR55 Q9Y2T6 3/20 0.53
SMPD1 P17405 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1082266 1.00 AKT1 (0.70) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL4565034 0.95 AKT1 (0.64) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL17416063 0.90 AKT1 (0.85) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL5446081 0.90 AKT1 (0.85) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL4199434 0.90 AKT1 (0.85) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL30898875 0.85 GPR55 (0.69) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL4601441 0.83 AKT1 (0.57) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL11131399 0.82 LPAR1 (0.56) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL13058680 0.82 AKT1 (0.58) AKT1AKT2AKT3PIK3R1PIK3CA
SCHEMBL11004956 0.80 PLCG2 (0.66) AKT1AKT2AKT3PIK3R1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-2429658-B1 Method for adjuvating the lipopolysaccharide (LPS) of gram-negative bacteria SANOFI PASTEUR (FR) 2016-04-20 EP disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
EP-2430151-B1 MENINGOCOCCAL VACCINE CONSTITUTED OF LIPOOLIGOSACCHARIDES FROM MODIFIED IMMUNOTYPE L6 NEISSERIA MENINIGITIDIS SANOFI PASTEUR (FR) 2014-06-18 EP disclosed
EP-2429576-A1 MENINGOCOCCAL VACCINE BASED ON LIPOOLIGOSACCHARIDE (LOS) AND NEISSERIA MENINGITIDIS PROTEIN Sanofi Pasteur (FR) 2012-03-21 EP disclosed
EP-2429658-A2 METHOD FOR ADMIXING THE LIPOPOLYSACCHARIDE (LPS) OF GRAM-NEGATIVE BACTERIA Sanofi Pasteur (FR) 2012-03-21 EP disclosed
EP-2430151-A2 MENIGOCOCCUS VACCINE CONTAINING LIPOOLIGOSACCHARIDE (LOS) FROM MODIFIED STRAINS OF L6 IMMUNOTYPE NEISSERIA MENINGITIDIS Sanofi Pasteur (FR) 2012-03-21 EP disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 US disclosed
WO-2010130899-A1 MENINGOCOCCAL VACCINE BASED ON LIPOOLIGOSACCHARIDE (LOS) AND NEISSERIA MENINGITIDIS PROTEIN SANOFI PASTEUR (FR) 2010-11-18 WO disclosed
WO-2010130898-A2 MENIGOCOCCUS VACCINE CONTAINING LIPOOLIGOSACCHARIDE (LOS) FROM MODIFIED STRAINS OF L6 IMMUNOTYPE NEISSERIA MENINGITIDIS SANOFI PASTEUR (FR) 2010-11-18 WO disclosed
WO-2010130896-A2 METHOD FOR ADMIXING THE LIPOPOLYSACCHARIDE (LPS) OF GRAM-NEGATIVE BACTERIA SANOFI PASTEUR (FR) 2010-11-18 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed
US-6042622-A Process for crystallization of alkali metal bicarbonate salts BASF CORPORATION (US) 2000-03-28 US disclosed
US-5716419-A Process for crystallization of mineral salts PPG INDUSTRIES, INC. (US) 1998-02-10 US disclosed