Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710211 | 0.89 | PLK1 (0.68) | PLK1HDAC2HDAC8HDAC6CA1 | |
| SCHEMBL8246095 | 0.77 | PLK1 (1.00) | PLK1HDAC2HDAC8HDAC6EPHX2 | |
| SCHEMBL1121661 | 0.76 | PLK1 (1.00) | PLK1HDAC2HDAC8HDAC6EPHX2 | |
| SCHEMBL14025527 | 0.76 | PLK1 (0.76) | PLK1HDAC2HDAC8HDAC6CA2 | |
| SCHEMBL6078477 | 0.75 | MEN1 (0.56) | PLK1HDAC6CA1CA2HPGD | |
| SCHEMBL21104562 | 0.75 | HDAC1 (0.60) | PLK1HDAC6CA1CA2EPHX2 | |
| SCHEMBL20300540 | 0.75 | L3MBTL1 (0.61) | PLK1HDAC2CA2HPGDTSHR | |
| SCHEMBL6958590 | 0.74 | PLK1 (1.00) | PLK1HDAC2HDAC8HDAC6HPGD | |
| SCHEMBL250247 | 0.73 | HDAC6 (0.80) | PLK1HDAC2HDAC8HDAC6CA2 | |
| SCHEMBL15017778 | 0.72 | PLK1 (0.70) | PLK1HDAC2HDAC8HDAC6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120062826-A1 | LIQUID CRYSTAL DEVICE, MANUFACTURING METHOD OF LIQUID CRYSTAL DEVICE, AND ELECTRONIC APPARATUS | SEIKO EPSON CORPORATION (JP) | 2012-03-15 | — | — | US | disclosed |