Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | DNA2 | P51530 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679988 | 0.84 | TSHR (0.63) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1549063 | 0.84 | TSHR (0.52) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| N,N-Dimethylethanaminium SCHEMBL3496715 | 0.79 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| N,N-Dimethylethanaminium SCHEMBL27698286 | 0.79 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| N,N-Dimethylethanaminium SCHEMBL15475254 | 0.79 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17746609 | 0.77 | TSHR (0.57) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3495423 | 0.77 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3495421 | 0.77 | TSHR (0.56) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL28146762 | 0.76 | ALDH1A1 (0.50) | TSHRTDP1ALDH1A1KDM4EKMT2A | |
| Trimethylammonium SCHEMBL28659606 | 0.76 | TSHR (0.64) | TSHRTDP1L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | CORBETT JEFFREY WAYNE | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | ACACA, PC, ACACB | TSHR 2108/4885TDP1 4606/4885L3MBTL1 2534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.