Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669529 | 0.94 | CYP3A4 (0.41) | GPR84CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9311177 | 0.82 | CYP1A2 (0.38) | GPR84CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9601311 | 0.79 | SOD1 (0.37) | PKM | |
| SCHEMBL9601315 | 0.79 | USP2 (0.42) | PKM | |
| SCHEMBL13180379 | 0.78 | — | — | |
| SCHEMBL8138860 | 0.76 | UTS2R (0.43) | GPR84UTS2R | |
| SCHEMBL27565006 | 0.76 | EPHX1 (0.52) | PKM | |
| SCHEMBL22957169 | 0.75 | — | — | |
| SCHEMBL22074334 | 0.74 | PKM (0.36) | CYP3A4CYP2C9PKMKCNH3 | |
| SCHEMBL13045345 | 0.69 | ESR1 (0.40) | CYP3A4CYP2C9PKMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4799951-A | 5-acylamino-pyrazole derivatives, composition containing them and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-24 | — | — | US | claimed |
| EP-0173821-B1 | SUBSTITUTED 5-AMINO-1-PHENYL PYRAZOLES | BAYER AG (DE) | 1989-01-18 | — | — | EP | claimed |
| US-4772309-A | 5-acylamino-pyrazoles, composition containing them, and herbicidal and plant growth regulating method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | claimed |
| US-4772310-A | 5-acylamino-pyrazole derivatives, composition containing them, and their use as herbicides and plant growth | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | claimed |
| EP-0248315-A2 | 5-Acylamino pyrazole derivatives | BAYER AG (DE) | 1987-12-09 | — | — | EP | claimed |
| EP-0190457-A1 | Derivatives of 3-methyl-imidazo [4,5-c]pyrazole having therapeutic activity and a process for the preparation theref | CAMILLO CORVI S.p.A. (IT) | 1986-08-13 | — | — | EP | claimed |
| EP-0173821-A1 | Substituted 5-amino-1-phenyl pyrazoles | BAYER AG (DE) | 1986-03-12 | — | — | EP | claimed |
| CN-103930109-B | The substituted heterocyclyl amides of N- | NOVARTIS AG (CH) | 2016-11-30 | — | — | CN | disclosed |
| US-7514561-B2 | Pesticidal 5-(acylamino) pyrazole derivatives | MERIAL LIMITED (US) | 2009-04-07 | — | — | US | disclosed |
| CN-1944413-A | Pesticidal 5- (acylamino) pyrazole derivatives | BAYER CROPSCIENCE SA (FR) | 2007-04-11 | — | — | CN | disclosed |
| US-20060135778-A1 | Pesticidal 5-(acylamino) pyrazole derivatives | BAYER CROPSCIENCE S.A. (FR) | 2006-06-22 | — | — | US | disclosed |
| CN-1719974-A | Pesticidal 5- (acylamino) pyrazole derivatives | BAYER CROPSCIENCE SA (FR) | 2006-01-11 | — | — | CN | disclosed |
| US-4931461-A | Pesticidal substituted 5-methylamino-1-arylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0248315-A2 | 5-Acylamino pyrazole derivatives | BAYER AG (DE) | 1987-12-09 | — | — | EP | disclosed |
| EP-0242573-A1 | 5-Acylamino-pyrazole derivatives | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| EP-0224019-A2 | 1-Aryl-4-nitropyrazole | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| EP-0190457-A1 | Derivatives of 3-methyl-imidazo [4,5-c]pyrazole having therapeutic activity and a process for the preparation theref | CAMILLO CORVI S.p.A. (IT) | 1986-08-13 | — | — | EP | disclosed |
| EP-0173821-A1 | Substituted 5-amino-1-phenyl pyrazoles | BAYER AG (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0068806-A2 | Basic acyl amides of (5-amino-1,3-dialkylpyrazol-4-yl)(aryl)methanones, processes for their production, and pharmaceutical compositions containing such compounds | WARNER-LAMBERT COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |
| US-3948878-A | FIBERS OF ACRYLONITRILE POLYMERS, POLYESTERS OR POLYAMIDES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135778-A1 | Pesticidal 5-(acylamino) pyrazole derivatives | AADAC, ACHE, AAAS | GPR84 4284/4885CYP1A2 77/4885CYP3A4 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.