Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952385 | 0.82 | KDM4E (0.40) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL27419938 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL28521655 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL29358471 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL8398555 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL2777 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL30100313 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL7897915 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL2561870 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Phthalic Acid SCHEMBL27618507 | 0.78 | ALDH1A1 (0.82) | ALDH1A1ALOX15KDM4EHPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655438-A2 | AGENTS, USES AND METHODS FOR TREATMENT | H. Lundbeck A/S (DK) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019016247-A2 | AGENTS, USES AND METHODS FOR TREATMENT | H. LUNDBECK A/S (DK) | 2019-01-24 | — | — | WO | disclosed |
| CN-108135986-A | Molecule based on antibody for the truncated Asp421 epitope specificities of Tau and their purposes in diagnose and treat Tau diseases | 纽约大学 | 2018-06-08 | — | — | CN | disclosed |
| CN-108137679-A | To Tau's{p}Ser404 the epitopes selectively molecule based on antibody and their purposes in diagnose and treat Tau diseases | 纽约大学 | 2018-06-08 | — | — | CN | disclosed |
| WO-2017070482-A2 | PSMA TARGETED RADIOHALOGENATED UREAS FOR CANCER RADIOTHERAPY | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-04-27 | — | — | WO | disclosed |
| EP-2072525-A1 | New polypeptides having affinity for HER2 | Affibody AB (SE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1259548-A1 | ANTIBODY SPECIFIC FOR THE ED-B DOMAIN OF FIBRONECTIN, CONJUGATES COMPRISING SAID ANTIBODY, AND THEIR USE FOR THE DETECTION AND TREATMENT OF ANGIOGENESIS | Eidgenössische Technische Hochschule Zürich (CH) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062800-A1 | ANTIBODY SPECIFIC FOR THE ED-B DOMAIN OF FIBRONECTIN, CONJUGATES COMPRISING SAID ANTIBODY, AND THEIR USE FOR THE DETECTION AND TREATMENT OF ANGIOGENESIS | Eidgenössische Technische Hochschule Zürich (CH) | 2001-08-30 | — | — | WO | disclosed |