Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.44 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064766 | 0.77 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4NR1H2NR1H3 | |
| SCHEMBL3605770 | 0.77 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4GPR119KCNH2 | |
| SCHEMBL4059662 | 0.77 | GPR119 (0.53) | SLC6A2SLC6A3SLC6A4GPR119 | |
| SCHEMBL4565249 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3605040 | 0.74 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4GPR119 | |
| SCHEMBL4058421 | 0.74 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4GPR119KCNH2 | |
| SCHEMBL20445846 | 0.74 | IL1B (0.43) | IL1BP2RX7NR1H2NR1H3 | |
| SCHEMBL29428225 | 0.74 | IL1B (0.43) | IL1BP2RX7NR1H2NR1H3 | |
| SCHEMBL3237401 | 0.73 | NR1H2 (0.43) | IL1BP2RX7NR1H2NR1H3 | |
| SCHEMBL4062683 | 0.73 | GPR119 (0.55) | SLC6A2SLC6A3SLC6A4GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |