Styrene

Styrene

SCHEMBL4565631

C=CCCC(=C)C(=O)OCCN.C=CCOC(=O)C=C.C=Cc1ccccc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
CYP3A4 P08684 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 3/20 0.34
TSHR P16473 3/20 0.34
HSD17B10 Q99714 2/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CASP1 P29466 3/20 0.33
APP P05067 1/20 0.32
IDO1 P14902 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4565701 0.88 MAPT (0.38) CYP3A4KDM4EMEN1MAPTKMT2A
Styrene SCHEMBL20186900 0.79 THRB (0.55) THRBCYP3A4MEN1KMT2ALMNA
Styrene SCHEMBL167641 0.79 CYP3A4 (0.51) THRBCYP3A4KDM4EMEN1MAPT
Styrene SCHEMBL9654658 0.77 CYP3A4 (0.44) THRBCYP3A4KDM4EMEN1MAPT
Styrene SCHEMBL10818757 0.77 CYP3A4 (0.46) THRBCYP3A4KDM4EMEN1MAPT
Styrene SCHEMBL3117319 0.77 CYP3A4 (0.49) THRBCYP3A4KDM4EMEN1MAPT
SCHEMBL4391880 0.77 MAPT (0.33) THRBCYP3A4MAPTLMNAALDH1A1
Styrene SCHEMBL3216401 0.75 MEN1 (0.45) THRBCYP3A4KDM4EMEN1MAPT
Styrene SCHEMBL8097534 0.75 MEN1 (0.47) THRBCYP3A4KDM4EMEN1MAPT
SCHEMBL5447947 0.74 TSHR (0.39) THRBCYP3A4MAPTMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US claimed
US-7632620-B2 Coated carrier XEROX CORPORATION (US) 2009-12-15 US disclosed
US-7452650-B2 Coated carriers and processes thereof XEROX CORPORATION (US) 2008-11-18 US disclosed
US-7374850-B2 Coated carriers XEROX CORPORATION (US) 2008-05-20 US disclosed
US-7374849-B2 Coated carrier XEROX CORPORATION (US) 2008-05-20 US disclosed
US-20060246369-A1 Coated carriers XEROX CORPORATION 2006-11-02 US disclosed
US-20060172218-A1 Coated carrier XEROX CORPORATION 2006-08-03 US disclosed
EP-1686428-A1 Coated carrier Xerox Corporation (US) 2006-08-02 EP disclosed
US-20060166124-A1 Coated carriers and processes thereof XEROX CORPORATION 2006-07-27 US disclosed
US-20060166125-A1 Coated carrier XEROX CORPORATION 2006-07-27 US disclosed
US-6132917-A Coated carrier XEROX CORPORATION (US) 2000-10-17 US disclosed
US-6051353-A REACTION PRODUCT OF GLYCIDYL METHACRYLATE POLYMER WITH AMINOALKYL OR (AMINOALKYL)AMINOALKYL METHACRYLATE POLYMER XEROX CORPORATION (US) 2000-04-18 US disclosed
US-6051354-A MIXING IN A HIGH SHEAR DEVICE A CARRIER CORE AND A CARRIER COATING, AND WHEREIN SAID HIGH SHEAR DEVICE CONTAINS IMPELLERS. XEROX CORPORATION (US) 2000-04-18 US disclosed
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US disclosed
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US disclosed
US-6037091-A Carrier with ferrocene containing polymer XEROX CORPORATION (US) 2000-03-14 US disclosed
US-6010812-A Coated carrier XEROX CORPORATION (US) 2000-01-04 US disclosed
US-6004712-A CORE AND THEREOVER A POLYMER OF (1) METHYLMETHACRYLATE AND A MONOALKYL AMINOALKYL METHACRYLATE, OR (2) A POLYMER OF METHYLMETHACRYLATE AND DIALKYLAMINOALKYL METHACRYLATE, TONER AND DEVELOPER XEROX CORPORATION (US) 1999-12-21 US disclosed
US-5945244-A Coated carrier XEROX CORPORATION (US) 1999-08-31 US disclosed
US-5935750-A A CARRIER COMPOSED OF A CORE AND A COATING OF A POLYMER CONTAINING QUTERNARY AMMONIUM SALT GROUP AND CONTAINS A CONDUCTIVE COMPONENT XEROX CORPORATION (US) 1999-08-10 US disclosed