Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565707 | 0.80 | MEN1 (0.55) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL2801723 | 0.78 | KMT2A (0.54) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL1056451 | 0.78 | KMT2A (1.00) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL1110180 | 0.76 | MDM4 (0.73) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL27874235 | 0.76 | KDR (0.63) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL12510751 | 0.76 | HDAC1 (0.67) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL4934571 | 0.75 | MEN1 (0.50) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL5178629 | 0.73 | HDAC1 (0.69) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL3299661 | 0.72 | ADORA1 (0.70) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL11831465 | 0.72 | MEN1 (0.64) | MEN1KMT2AMAPTTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048889-A1 | Use of non-competitive and selective glur5 antagonists as gultamate receptor modulating compounds | NEUROSEARCH A/S (DK) | 2004-03-11 | — | — | US | claimed |
| EP-1355640-A1 | USE OF NON-COMPETITIVE AND SELECTIVE GLUR5 ANTAGONISTS AS GLUTAMATE RECEPTOR MODULATING COMPOUNDS | NEUROSEARCH A/S (DK) | 2003-10-29 | — | — | EP | claimed |
| WO-2002058691-A1 | USE OF NON-COMPETITIVE AND SELECTIVE GLUR5 ANTAGONISTS AS GLUTAMATE RECEPTOR MODULATING COMPOUNDS | NEUROSEARCH A/S (DK) | 2002-08-01 | — | — | WO | claimed |
| US-7488756-B2 | Use of non-competitive and selective GluR5 antagonists as glutamate receptor modulating compounds | NEUROSEARCH A/S (DK) | 2009-02-10 | — | — | US | disclosed |
| US-20040048889-A1 | Use of non-competitive and selective glur5 antagonists as gultamate receptor modulating compounds | NEUROSEARCH A/S (DK) | 2004-03-11 | — | — | US | disclosed |
| EP-1355640-A1 | USE OF NON-COMPETITIVE AND SELECTIVE GLUR5 ANTAGONISTS AS GLUTAMATE RECEPTOR MODULATING COMPOUNDS | NEUROSEARCH A/S (DK) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002058691-A1 | USE OF NON-COMPETITIVE AND SELECTIVE GLUR5 ANTAGONISTS AS GLUTAMATE RECEPTOR MODULATING COMPOUNDS | NEUROSEARCH A/S (DK) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048889-A1 | Use of non-competitive and selective glur5 antagonists as gultamate receptor modulating compounds | GRM5, GRIK5, GRIN1 | MEN1 4791/4885KMT2A 1332/4885PKM 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.