SCHEMBL12510751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5178629	0.94	HDAC1 (0.69)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL4214042	0.88	KCNMA1 (0.67)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL12432053	0.84	KCNMA1 (0.67)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL22905311	0.83	HDAC1 (0.71)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL10011045	0.83	KCNMA1 (0.57)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL2380752	0.83	HDAC1 (0.71)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL30799070	0.82	HDAC1 (0.55)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL7817331	0.82	HDAC1 (0.69)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL14740985	0.82	HCAR3 (0.61)	HDAC1KCNMA1HDAC2KMT2APKM
	SCHEMBL27383786	0.82	HDAC1 (0.55)	HDAC1KCNMA1HDAC2KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.