Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617314 | 0.74 | MAOB (0.58) | PTGER1MAOAMAOBESR1ESR2 | |
| SCHEMBL10549752 | 0.74 | PTGER1 (0.55) | PTGER1ESR1ESR2 | |
| SCHEMBL3203406 | 0.73 | PTGER1 (0.59) | PTGER1 | |
| Biphenyl SCHEMBL3384157 | 0.70 | LMNA (0.87) | LMNANAPRTP4HTML3MBTL1TLR7 | |
| 2-Picolinic Acid SCHEMBL28737691 | 0.70 | LMNA (0.95) | LMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL31346189 | 0.70 | MAOB (0.69) | PTGER1MAOAMAOBESR1ESR2 | |
| 2-Picolinic Acid SCHEMBL674837 | 0.68 | LMNA (1.00) | LMNANAPRTP4HTML3MBTL1 | |
| 2-Picolinic Acid SCHEMBL36055 | 0.68 | — | — | |
| 2-Picolinic Acid SCHEMBL7457912 | 0.68 | LMNA (1.00) | LMNANAPRTP4HTML3MBTL1 | |
| 2-Picolinic Acid SCHEMBL28737810 | 0.68 | LMNA (1.00) | LMNANAPRTP4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129670-A2 | BENZOFURAN COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY THE ACTION OF PGE2 AT THE EP1 RECEPTOR | Glaxo Group Limited (GB) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008098978-A2 | BENZOFURAN COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MEDIATED BY THE ACTION OF PGE2 AT THE EP1 RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-08-21 | — | — | WO | disclosed |