Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5538611 | 0.73 | AKR1C1 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL6926723 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL13626300 | 0.69 | POLB (0.61) | ALDH1A1POLBAKR1C1HDAC4KDM4E | |
| SCHEMBL11692509 | 0.67 | POLB (0.60) | ALDH1A1POLBAKR1C1HDAC4KDM4E | |
| SCHEMBL4590449 | 0.66 | MEN1 (0.40) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL20738594 | 0.66 | POLB (0.61) | ALDH1A1POLBAKR1C1HDAC4KDM4E | |
| SCHEMBL2261830 | 0.65 | AKR1C1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL5987740 | 0.65 | POLB (0.65) | ALDH1A1MEN1KMT2APOLBAKR1C1 | |
| SCHEMBL4984844 | 0.64 | SLC6A4 (0.38) | ALDH1A1MEN1KMT2APOLBAKR1C1 | |
| SCHEMBL23382983 | 0.63 | AKR1C1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270394-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | ZALICUS PHARMACEUTICALS LTD. (CA) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270394-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CACNA1G, CACNA1H, CACNA1I | ALDH1A1 4034/4885MEN1 2191/4885KMT2A 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.