Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169922 | 0.87 | MCL1 (0.49) | HPGDPOLBALDH1A1CYP2C19HTT | |
| SCHEMBL27351823 | 0.82 | HPGD (0.51) | HPGDPOLBALDH1A1CYP2C19HTT | |
| SCHEMBL29723381 | 0.80 | HPGD (0.56) | HPGDPOLBALDH1A1CYP2C19L3MBTL3 | |
| SCHEMBL21132553 | 0.80 | HPGD (0.56) | HPGDPOLBALDH1A1CYP2C19L3MBTL3 | |
| SCHEMBL26144962 | 0.78 | SRD5A2 (0.59) | KMOHPGDALDH1A1L3MBTL3APEX1 | |
| SCHEMBL4322056 | 0.76 | KDM4E (0.47) | HPGDPOLBALDH1A1HTTKDM4E | |
| SCHEMBL7167323 | 0.76 | MCL1 (0.46) | HPGDPOLBALDH1A1CYP2C19HTT | |
| SCHEMBL9389800 | 0.76 | ALDH1A1 (0.54) | HPGDPOLBALDH1A1CYP2C19MEN1 | |
| SCHEMBL26144964 | 0.75 | SRD5A2 (0.54) | KMOHPGDALDH1A1L3MBTL3APEX1 | |
| SCHEMBL31286068 | 0.74 | KMO (0.51) | KMOHPGDL3MBTL3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |