Benzoquinone

Benzoquinone

SCHEMBL456644

COC.O=C1C=CC(=O)C=C1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.67
ALDH1A1 P00352 4/20 0.67
MAPK1 P28482 3/20 0.67
RECQL P46063 2/20 0.67
POLB P06746 2/20 0.67
BLM P54132 2/20 0.67
BCHE P06276 1/20 0.67
MAOA P21397 1/20 0.67
ACHE P22303 1/20 0.67
MAOB P27338 1/20 0.67
APEX1 P27695 1/20 0.67
CASP1 P29466 1/20 0.67
MDM2 Q00987 1/20 0.67
DHODH Q02127 1/20 0.67
HSD17B10 Q99714 1/20 0.67
APOBEC3G Q9HC16 1/20 0.67
ERBB2 P04626 1/20 0.48
MIF P14174 1/20 0.39
KDM4E B2RXH2 6/20 0.38
MEN1 O00255 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL28597092 0.82 ALDH1A1 (0.80) TDP1ALDH1A1MAPK1RECQLPOLB
Benzoquinone SCHEMBL5695835 0.82 TDP1 (0.54) TDP1ALDH1A1MAPK1RECQLPOLB
Benzoquinone SCHEMBL10506648 0.82 ALDH1A1 (1.00) TDP1ALDH1A1MAPK1RECQLPOLB
Benzoquinone SCHEMBL18103 0.82
Benzoquinone SCHEMBL3208089 0.82
Benzoquinone SCHEMBL30679171 0.82
Benzoquinone SCHEMBL5308519 0.82 ALDH1A1 (1.00) TDP1ALDH1A1MAPK1RECQLPOLB
Benzoquinone SCHEMBL460082 0.82 ALDH1A1 (1.00) TDP1ALDH1A1MAPK1RECQLPOLB
Benzoquinone SCHEMBL11661862 0.78 ALDH1A1 (0.73) TDP1ALDH1A1MAPK1RECQLPOLB
Benzoquinone SCHEMBL9457254 0.78 TDP1 (0.73) TDP1ALDH1A1MAPK1RECQLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128644-A A kind of biodegradable polycarbonate-polyester copolymer and preparation method thereof 中国科学院成都有机化学有限公司 2019-08-16 CN claimed
CN-108473412-A Method for purifying (meth) acrylic esters 阿肯马法国公司 2018-08-31 CN claimed
CN-103059282-B Biodegradable aliphatic polyester homopolymer containing double bond and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2016-02-10 CN claimed
CN-103059310-B Double-bond-containing biodegradable polyester multi-block copolymer and preparation method thereof CHINESE ACAD INST CHEMISTRY 2015-04-29 CN claimed
CN-103059310-A Double-bond-containing biodegradable polyester multi-block copolymer and preparation method thereof CHINESE ACAD INST CHEMISTRY 2013-04-24 CN claimed
CN-103059282-A Biodegradable aliphatic polyester homopolymer containing double-bond and preparation method thereof CHINESE ACAD INST CHEMISTRY 2013-04-24 CN claimed
CN-116323670-A Antibodies specific for alpha-1, 6-core-fucosylated PSAs and fucosylated fragments thereof 豪夫迈·罗氏有限公司 2023-06-23 CN disclosed
CN-110128644-A A kind of biodegradable polycarbonate-polyester copolymer and preparation method thereof 中国科学院成都有机化学有限公司 2019-08-16 CN disclosed
CN-109996798-A N- [5- (aminosulfonyl) -4-methyl-1, 3-thiazol-2-yl ] -N-methyl-2- [4- (2-pyridinyl) -phenyl ] -acetamide free base hemihydrate, method for the production and use thereof 艾库里斯抗感染治疗有限公司 2019-07-09 CN disclosed
CN-103059282-B Biodegradable aliphatic polyester homopolymer containing double bond and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2016-02-10 CN disclosed
CN-103059310-B Double-bond-containing biodegradable polyester multi-block copolymer and preparation method thereof CHINESE ACAD INST CHEMISTRY 2015-04-29 CN disclosed
EP-2809760-A1 PROCESS FOR REDUCING MALODOURS Henkel AG&Co. KGAA (DE) 2014-12-10 EP disclosed
CN-103936975-A Sulfonate-anion-functionalized biodegradable polyester and preparation method thereof CHINESE ACAD INST CHEMISTRY 2014-07-23 CN disclosed
CN-1258517-C Process for preparing acrylic ester (methacrylic) DSM IP PROPERTY N V (NL) 2006-06-07 CN disclosed
WO-2005093034-A1 MULTI-PHASE TABLETS WITH AN IMPROVED SENSATION OF FRAGRANCE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-10-06 WO disclosed
US-6838515-B2 Process for the preparation of esters of (meth)acrylic acid DSM IP ASSETS B.V. (NL) 2005-01-04 US disclosed
EP-1353893-A1 PROCESS FOR THE PREPARATION OF ESTERS OF (METH)ACRYLIC ACID Dsm N.V. (NL) 2003-10-22 EP disclosed
CN-1434020-A Process for preparing acrylic ester (methacrylic) DSM NV (NL) 2003-08-06 CN disclosed
US-20020156317-A1 Process for the preparation of esters of (meth)acrylic acid DSM IP ASSETS B.V. (NL) 2002-10-24 US disclosed
WO-2002055473-A1 PROCESS FOR THE PREPARATION OF ESTERS OF (METH)ACRYLIC ACID DSM IP ASSETS B.V. (NL) 2002-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156317-A1 Process for the preparation of esters of (meth)acrylic acid ADH1A, PAM, OXGR1 TDP1 3600/4885ALDH1A1 181/4885MAPK1 2437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.