Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235983 | 0.82 | IDO1 (0.37) | IDO1ALOX5APFEN1GAAMAPT | |
| SCHEMBL3245397 | 0.78 | IDO1 (0.39) | IDO1ALOX5APFEN1KMT2AGAA | |
| SCHEMBL3240159 | 0.68 | IDO1 (0.38) | IDO1ALOX5APFEN1KMT2AMEN1 | |
| SCHEMBL3242799 | 0.67 | SMN1; SMN2 (0.44) | KMT2AMEN1 | |
| SCHEMBL3237976 | 0.66 | ALDH1A1 (0.37) | IDO1KMT2AMEN1MAPTPKM | |
| SCHEMBL3247001 | 0.65 | INPPL1 (0.39) | IDO1KMT2APOLBGAAMEN1 | |
| SCHEMBL3244047 | 0.65 | CRHBP (0.34) | KMT2APOLBGAA | |
| SCHEMBL4330265 | 0.65 | IDO1 (0.37) | IDO1ALOX5APFEN1PNMT | |
| SCHEMBL3242221 | 0.65 | CNR1 (0.38) | KMT2APOLBMEN1MAPT | |
| SCHEMBL3240374 | 0.65 | KMT2A (0.39) | KMT2APOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131958-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING TRIAZINE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | claimed |