Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240159 | 0.78 | IDO1 (0.38) | IDO1ALOX5APFEN1PDCD1CD274 | |
| SCHEMBL3232764 | 0.67 | P2RX7 (0.37) | IDO1PNMTP2RX7 | |
| SCHEMBL4566690 | 0.65 | IDO1 (0.35) | IDO1ALOX5APFEN1PNMT | |
| SCHEMBL3235983 | 0.64 | IDO1 (0.37) | IDO1ALOX5APFEN1PNMTCARM1 | |
| SCHEMBL995345 | 0.62 | IDO1 (0.69) | IDO1PNMTCARM1KDM4EP2RX7 | |
| SCHEMBL3245397 | 0.61 | IDO1 (0.39) | IDO1ALOX5APFEN1PNMTCARM1 | |
| SCHEMBL547586 | 0.59 | IDO1 (0.69) | IDO1PNMTCARM1KDM4E | |
| SCHEMBL5085295 | 0.58 | CNR2 (0.54) | IDO1CNR2P2RX7 | |
| SCHEMBL12877184 | 0.58 | IDO1 (0.67) | IDO1PNMTCARM1KDM4EP2RX7 | |
| SCHEMBL3302008 | 0.57 | PNMT (0.68) | IDO1PNMTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131947-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING PYRIDAZINE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |