Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 17/20 | 0.32 |
| ▸ | CA9 | Q16790 | 16/20 | 0.32 |
| ▸ | CA1 | P00915 | 16/20 | 0.32 |
| ▸ | CA12 | O43570 | 5/20 | 0.31 |
| ▸ | CA7 | P43166 | 5/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.31 |
| ▸ | CA3 | P07451 | 4/20 | 0.31 |
| ▸ | CA4 | P22748 | 4/20 | 0.31 |
| ▸ | CA6 | P23280 | 4/20 | 0.31 |
| ▸ | CA5A | P35218 | 4/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Busulfan SCHEMBL27648820 | 0.79 | ALDH1A1 (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1100211 | 0.79 | CA1 (0.43) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL28854542 | 0.79 | CA2 (0.32) | CA2 | |
| Busulfan SCHEMBL29446043 | 0.79 | TSHR (0.83) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL1606138 | 0.78 | TSHR (0.65) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18092593 | 0.78 | CA1 (0.44) | TSHRCA2CA9CA1CA12 | |
| Ethane SCHEMBL27476144 | 0.76 | — | — | |
| SCHEMBL11176516 | 0.76 | TSHR (0.62) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL9432188 | 0.76 | TSHR (0.62) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL20495987 | 0.76 | TSHR (0.62) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2769 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190048087-A9 | Fully Human Antibodies that Bind to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) | SORRENTO THERAPEUTICS, INC. (US) | 2019-02-14 | — | — | US | claimed |
| EP-2830663-B1 | FULLY HUMAN ANTIBODIES THAT BIND TO VEGFR2 | SORRENTO THERAPEUTICS INC (US) | 2019-02-06 | — | — | EP | claimed |
| US-20170166644-A1 | Fully Human Antibodies that Bind to VEGFR2 | SORRENTO THERAPEUTICS, INC. (US) | 2017-06-15 | — | — | US | claimed |
| US-9029510-B2 | Fully human antibodies that bind to VEGFR2 and methods of use thereof | SORRENTO THERAPEUTICS, INC. (US) | 2015-05-12 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-2830663-A2 | FULLY HUMAN ANTIBODIES THAT BIND TO VEGFR2 | Sorrento Therapeutics Inc. (US) | 2015-02-04 | — | — | EP | claimed |
| US-20140294827-A1 | Fully Human Antibodies that Bind to VEGFR2 | VIVASOR, INC. | 2014-10-02 | — | — | US | claimed |
| WO-2013149219-A2 | FULLY HUMAN ANTIBODIES THAT BIND TO VEGFR2 | SORRENTO THERAPEUTICS INC. (US) | 2013-10-03 | — | — | WO | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-20070082020-A1 | Blood clot filter having coating | PICCONE VINCENT A JR | 2007-04-12 | — | — | US | claimed |
| US-20240238081-A1 | EVERTING TRANSCATHETER VALVE AND METHODS | EDWARDS LIFESCIENCES CORPORATION | 2024-07-18 | — | — | US | disclosed |
| EP-3914269-B1 | ANTIBODIES SPECIFIC TO DELTA 1 CHAIN OF T CELL RECEPTOR | UNIV NEW YORK (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2024148073-A1 | HYDRATION COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | Ripplewell, Inc. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-20240225868-A9 | MULTI-COMPONENT DELIVERY SYSTEMS AND METHODS | W. L. GORE & ASSOCIATES, INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240218069-A1 | BI-SPECIFIC ANTIBODIES COMPRISING ANTI-B7H3 BINDING MOLECULES | LYVGEN BIOPHARMA HOLDINGS LIMITED (KY) | 2024-07-04 | — | — | US | disclosed |
| WO-2001085064-A1 | MULTILAYER STENTS HAVING ENHANCED FLEXIBILITY AND HOOP STRENGTH | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2001-11-15 | — | — | WO | disclosed |
| US-6153252-A | Process for coating stents | ETHICON, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| CN-1248177-A | Coated particles, method of making and using | SELECT RELEASE L C (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0970711-A2 | Process for coating stents | Ethicon, Inc. (US) | 2000-01-12 | — | — | EP | disclosed |
| US-4975421-A | WATER SOLUBLE, IMPREGNATED IN A VEHICLE FOR TOPICAL APPLICATION; MICROBIOCIDES | BIOGLUCAN, LP. (US) | 1990-12-04 | — | — | US | disclosed |