Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | MMP9 | P14780 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 11/20 | 0.43 |
| ▸ | CA9 | Q16790 | 11/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 10/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432188 | 0.98 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL8723938 | 0.98 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL11176516 | 0.98 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL20495987 | 0.98 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL1606611 | 0.98 | TSHR (0.62) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL6621065 | 0.93 | ALDH1A1 (0.61) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL2241904 | 0.91 | TSHR (0.54) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL11250193 | 0.88 | LMNA (0.50) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL11250191 | 0.88 | LMNA (0.50) | TSHRALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL13812658 | 0.87 | ALDH1A1 (0.48) | TSHRALDH1A1LMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100528829-C | Metathesis synthesis of pheromones or components thereof | R L PEDERSON R H GRUBBS (US) | 2009-08-19 | — | — | CN | claimed |
| WO-2015006740-A2 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-15 | — | — | WO | disclosed |
| US-20110082312-A1 | PRODUCTION OF COMPOUNDS COMPRISING CF30 GROUPS | MERCK PATENT GESELLSCHAFT MIT DESCHRANKTER HAFTUNG (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20110082312-A1 | PRODUCTION OF COMPOUNDS COMPRISING CF30 GROUPS | MERCK PATENT GESELLSCHAFT MIT DESCHRANKTER HAFTUNG (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20100196316-A1 | CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION | ENANTA PHARMACEUTICALS, INC. | 2010-08-05 | — | — | US | disclosed |
| US-20090203631-A1 | PEPTIDE DEFORMYLASE INHIBITORS AS NOVEL ANTIBIOTICS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-08-13 | — | — | US | disclosed |
| US-7538085-B2 | Macrocyclic peptide antibiotics; drug resistant, drug sensitive bacterial infections | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-05-26 | — | — | US | disclosed |
| US-20070259812-A1 | Peptide deformylase inhibitors as novel antibiotics | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION | 2007-11-08 | — | — | US | disclosed |
| US-7208595-B2 | Peptide deformylase inhibitors as novel antibiotics | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-04-24 | — | — | US | disclosed |
| US-20050026821-A1 | Peptide deformylase inhibitors as novel antibiotics | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-02-03 | — | — | US | disclosed |
| WO-2000015613-A1 | METHOD OF MAKING TERTIARY HINDERED AMINES | ARISTECH CHEMICAL CORPORATION (US) | 2000-03-23 | — | — | WO | disclosed |
| US-5856491-A | REACTING SECONDARY AMINE WITH TERMINALLY UNSATURATED ELECTROPHILIC COMPOUND IN PRESENCE OF N-METHYLPYRROLIDINONE SOLVENT | ARISTECH CHEMICAL CORP. (US) | 1999-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203631-A1 | PEPTIDE DEFORMYLASE INHIBITORS AS NOVEL ANTIBIOTICS | PDF, PADI3, PADI6 | TSHR 3070/4885ALDH1A1 4009/4885LMNA 2917/4885 |
| US-20110082312-A1 | PRODUCTION OF COMPOUNDS COMPRISING CF30 GROUPS | ZRANB2, ORC3, IKZF2 | TSHR 2163/4885ALDH1A1 3861/4885LMNA 4449/4885 |
| US-20100196316-A1 | CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION | HAVCR2, CHP1, PTPRC | TSHR 4846/4885ALDH1A1 3391/4885LMNA 3948/4885 |
| US-20070259812-A1 | Peptide deformylase inhibitors as novel antibiotics | PDF, PADI3, PADI6 | TSHR 3070/4885ALDH1A1 4009/4885LMNA 2917/4885 |
| US-20050026821-A1 | Peptide deformylase inhibitors as novel antibiotics | PDF, PADI3, PADI6 | TSHR 3070/4885ALDH1A1 4009/4885LMNA 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.