SCHEMBL4567216

SCHEMBL4567216

CCCCCCCC/C=C/CCCCCN

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
ALDH1A1 P00352 1/20 0.68
TSHR P16473 1/20 0.68
EPHX1 P07099 1/20 0.68
FAAH O00519 3/20 0.58
TRPV1 Q8NER1 1/20 0.58
SLC6A5 Q9Y345 2/20 0.58
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
SOAT1 P35610 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11855522 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Dectaflur SCHEMBL20875746 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL11850135 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Dectaflur SCHEMBL21052121 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL25409164 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21060609 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL23621182 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL22677777 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Dectaflur SCHEMBL21052097 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR
Dectaflur SCHEMBL21052096 1.00 DNM1 (0.68) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017726-B2 Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-28 US disclosed
US-9017726-B2 Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-28 US disclosed
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF Korean Institute of Science and Technology of Seoul, Republic of Korea 2012-05-17 US disclosed
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF Korean Institute of Science and Technology of Seoul, Republic of Korea 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF PHOSPHO1, HSPA2, FEM1B DNM1 3966/4885MEN1 168/4885KMT2A 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.