SCHEMBL456737

SCHEMBL456737

C=CCc1nc(CC=C)nc(CC=C)n1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9280230 0.86 ALDH1A1 (0.35) ALDH1A1ALOX15TSHR
SCHEMBL369674 0.86 CASP1 (0.40) NPSR1
SCHEMBL9403160 0.80 LMNA (0.40) ALDH1A1
SCHEMBL5485611 0.80 CDC7 (0.30)
SCHEMBL3809971 0.80 ALDH1A1 (0.42) ALDH1A1ALOX15TSHR
SCHEMBL7901999 0.80
SCHEMBL11448540 0.80
SCHEMBL18120869 0.80 GAA (0.33) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL486583 0.80 CASP1 (0.46) SMN1; SMN2NPSR1
SCHEMBL11119104 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650187-A1 DECORATED WALL OR FLOOR PANEL Akzenta Paneele + Profile GmbH (DE) 2025-11-19 EP claimed
WO-2024123163-A1 BIODEGRADABLE SENSOR FOR PRESSURE MEASUREMENT AND METHOD FOR MANUFACTURING SAME 고려대학교 산학협력단 2024-06-13 WO claimed
US-20240066185-A1 MULTILAYERED VASCULARIZED CONSTRUCT UNIVERSITY OF WASHINGTON (US) 2024-02-29 US claimed
CN-117258543-A Method for constructing antibiotic desalination nanofiltration membrane based on knife coating method assisted interfacial polymerization 新疆大学 2023-12-22 CN claimed
CN-111641383-B Preparation method and application of amorphous silicon flat-plate type fluorescent solar collector 宁波大学 2023-04-11 CN claimed
CN-114773671-A Spray drying preparation method of methyl octabromoether microcapsule and flame-retardant XPS material thereof 北京工商大学 2022-07-22 CN claimed
WO-2022076490-A1 GEOMETRICALLY DEFINED ACTUATION FOR A MECHANICALLY ACTIVE ORGAN-ON-A-CHIP THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-14 WO claimed
CN-114085429-A Microcapsule flame retardant and preparation method and application thereof 北京普利宏斌化工材料有限责任公司 2022-02-25 CN claimed
CN-112852015-A Composite brominated flame retardant with high thermal stability and efficient flame-retardant polystyrene foam material thereof 北京工商大学 2021-05-28 CN claimed
US-20210002493-A1 ZWITTERIONIC MONOMERS, POLYZWITTERIONIC POLYMERS FORMED THEREFROM, SURFACE FUNCTIONALIZATION AND SURFACE MODIFICATION TRELLEBORG SEALING SOLUTIONS PLYMOUTH, LLC 2021-01-07 US claimed
WO-2015033182-A1 SELF-HEALING TRANSPARENT POLYMER COMPOSITIONS CONTAINING CONDUCTIVE COLLOIDS ESSILOR (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2015-03-12 WO claimed
US-20120296021-A1 N-ALLYL CARBAMATE COMPOUNDS AND USE THEREOF, IN PARTICULAR IN RADIATION-CURING COATINGS FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V (DE) 2012-11-22 US claimed
EP-2507207-A2 N-ALLYL CARBAMATE COMPOUNDS AND THE USE THEREOF, IN PARTICULAR FOR RADIATION-CURED COATINGS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2012-10-10 EP claimed
US-20120189896-A1 ELECTRODE SEPARATOR ZPOWER, LLC (US) 2012-07-26 US claimed
EP-2412048-A1 ELECTRODE SEPARATOR ZPower, LLC (US) 2012-02-01 EP claimed
WO-2011067183-A2 N-ALLYL CARBAMATE COMPOUNDS AND THE USE THEREOF, IN PARTICULAR FOR RADIATION-CURED COATINGS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2011-06-09 WO claimed
WO-2010111087-A1 ELECTRODE SEPARATOR ZPOWER, INC. (US) 2010-09-30 WO claimed
EP-2172230-A2 Lubricious eluting polymer blend and coating made from the same Cardiac Pacemakers, Inc. (US) 2010-04-07 EP claimed
EP-2121063-A2 METHOD OF FORMATION OF VISCOUS, SHAPE CONFORMING GELS AND THEIR USES AS MEDICAL PROSTHESIS Uluru Inc. (US) 2009-11-25 EP claimed
WO-2008112705-A2 METHOD OF FORMATION OF VISCOUS, SHAPE CONFORMING GELS AND THEIR USES AS MEDICAL PROSTHESIS ULURU, INC. (US) 2008-09-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296021-A1 N-ALLYL CARBAMATE COMPOUNDS AND USE THEREOF, IN PARTICULAR IN RADIATION-CURING COATINGS C9, ERCC1, C5 ALDH1A1 441/4885TP53 4218/4885CYP3A4 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.