Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454919 | 0.80 | ESR2 (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL457353 | 0.75 | PDE4D (0.33) | ALDH1A1MAPTNPSR1HRH1 | |
| SCHEMBL10428951 | 0.72 | BACE1 (0.36) | MEN1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL7814278 | 0.69 | CYP2A6 (0.41) | MEN1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL456919 | 0.69 | ALDH1A1 (0.41) | MEN1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL14675940 | 0.69 | ESR2 (0.38) | MEN1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL16393627 | 0.66 | BRD4 (0.51) | ALDH1A1HPGDHSD17B10BRD4 | |
| SCHEMBL457978 | 0.66 | TP53 (0.32) | MEN1MAPTHPGDTSHRKMT2A | |
| SCHEMBL10091277 | 0.65 | PDK2 (0.36) | KDM4EMEN1ALDH1A1KMT2ABRD4 | |
| SCHEMBL16467910 | 0.65 | ABCB1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |