Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 10/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060820 | 0.93 | USP2 (0.40) | ALDH1A1TSHRUSP2CA1PAOX | |
| SCHEMBL6824546 | 0.84 | USP2 (0.35) | ALDH1A1USP2PAOX | |
| SCHEMBL12153331 | 0.83 | CA1 (0.48) | ALDH1A1CA1 | |
| SCHEMBL25468996 | 0.83 | LTA4H (0.50) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL8062393 | 0.83 | LTA4H (0.50) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL12153332 | 0.81 | CA1 (0.46) | CA1 | |
| SCHEMBL28693236 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRUSP2CA1DNM1 | |
| SCHEMBL14610975 | 0.81 | ACE2 (0.50) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL14569702 | 0.81 | ACE2 (0.50) | ALDH1A1TSHRKDM4AKDM4CKDM5A | |
| SCHEMBL8213505 | 0.81 | ACE2 (0.50) | ALDH1A1TSHRKDM4AKDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9078929-B2 | ε-Polylysine conjugates and the use thereof | MERCK PATENT GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-20120122788-A1 | E-POLYLYSINE CONJUGATES AND THE USE THEREOF | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122788-A1 | E-POLYLYSINE CONJUGATES AND THE USE THEREOF | LNPEP, EEA1, DNPEP | ALDH1A1 3963/4885TSHR 4074/4885USP2 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.