Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12296823 | 0.97 | L3MBTL1 (0.50) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL822744 | 0.91 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL12761668 | 0.86 | L3MBTL1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL12761682 | 0.86 | L3MBTL1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL12761678 | 0.85 | L3MBTL1 (0.44) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL17883125 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL7041520 | 0.85 | HSD17B10 (0.56) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL12761674 | 0.85 | L3MBTL1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL12761675 | 0.85 | L3MBTL1 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL12761691 | 0.84 | NTRK1 (0.40) | ALDH1A1LMNASMN1; SMN2KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | PTGER1, CYSLTR1, LTB4R | ALDH1A1 422/4885LMNA 4472/4885SMN1; SMN2 4661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.