SCHEMBL4569166

SCHEMBL4569166

CC(C)(C)OC(=O)NCC(O)Cc1cccc(OCC2CCCCC2)c1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.43
ACACB O00763 1/20 0.43
ACACA Q13085 1/20 0.43
CACNA1B Q00975 2/20 0.42
CETP P11597 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.42
ADAM17 P78536 1/20 0.41
KAT6A Q92794 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818794 1.00 SLC2A1 (0.43) SLC2A1ACACBACACACACNA1BCETP
SCHEMBL2207739 0.90 CETP (0.43) SLC2A1ACACBACACACACNA1BCETP
SCHEMBL2210867 0.85 SIRT2 (0.46) SLC2A1ACACBACACACETPSIRT2
SCHEMBL2206351 0.84 MTNR1A (0.48) ACACBACACASIRT2ADAM17KAT6A
SCHEMBL2206355 0.84 MTNR1A (0.48) ACACBACACASIRT2ADAM17KAT6A
SCHEMBL2208551 0.84 MTNR1A (0.48) ACACBACACASIRT2ADAM17KAT6A
SCHEMBL3135305 0.83 EPHX1 (0.40) ACACB
Hydrochloric Acid SCHEMBL2207028 0.83 MTNR1A (0.47) ACACBACACASIRT2ADAM17KAT6A
SCHEMBL4569164 0.83 SLC2A1 (0.44) SLC2A1ACACBACACACACNA1BSIRT2
Hydrochloric Acid SCHEMBL2207026 0.83 MTNR1A (0.47) ACACBACACASIRT2ADAM17KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2023-07-13 US disclosed
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2021-03-18 US disclosed
US-10639286-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2020-05-05 US disclosed
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2019-06-20 US disclosed
US-10188615-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2019-01-29 US disclosed
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2018-06-28 US disclosed
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. 2018-06-28 US disclosed
EP-3210966-A1 ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Acucela, Inc. (US) 2017-08-30 EP disclosed
US-9737496-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2017-08-22 US disclosed
US-9737496-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2017-08-22 US disclosed
US-8829244-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2014-09-09 US disclosed
US-8829244-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2014-09-09 US disclosed
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA, INC. (US) 2013-08-01 US disclosed
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA, INC. (US) 2013-08-01 US disclosed
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-08-23 US disclosed
US-20120129894-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-24 US disclosed
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ACUCELA INC. (US) 2012-05-17 US disclosed
US-7982071-B2 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2011-07-19 US disclosed
US-20090326074-A1 Alkoxy compounds for disease treatment ACUCELA INC. (US) 2009-12-31 US disclosed
WO-2009045479-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ACUCELA INC. (US) 2009-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122938-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20210077427-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20230218549-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER SLC2A1 891/4885ACACB 142/4885ACACA 236/4885
US-20190183816-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20130197096-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20120214852-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20090326074-A1 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-10188615-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20180177746-A1 ALKOXY COMPOUNDS FOR DISEASE TREATMENT ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-20120129894-A1 Alkoxy Compounds for Disease Treatment ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885
US-10639286-B2 Alkoxy compounds for disease treatment ALDH1A2, CLN6, AGER SLC2A1 911/4885ACACB 139/4885ACACA 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.