Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 16/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 16/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10175736 | 0.85 | RXRA (0.40) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 | |
| SCHEMBL11994362 | 0.80 | RXRA (0.40) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 | |
| SCHEMBL4569949 | 0.79 | RXRA (0.40) | RXRAGRIN1GRIN2BCHRNA7 | |
| SCHEMBL19821670 | 0.78 | GPR55 (0.34) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 | |
| SCHEMBL19821720 | 0.75 | KDM4E (0.35) | RXRAGRIN1GRIN2BALDH1A1 | |
| SCHEMBL11994370 | 0.73 | CYP1A2 (0.46) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 | |
| SCHEMBL19822069 | 0.73 | RXRA (0.34) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 | |
| SCHEMBL12394763 | 0.73 | HRH4 (0.40) | RXRAGRIN1GRIN2BALDH1A1 | |
| SCHEMBL21705891 | 0.72 | RXRA (0.35) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 | |
| SCHEMBL3507581 | 0.72 | TLR9 (0.38) | RXRAGRIN1GRIN2BALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122679-A1 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122679-A1 | MESOIONIC PESTICIDES | CHRM2, CHRM5, CHRM1 | RXRA 189/4885GRIN1 141/4885GRIN2B 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.