Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549769 | 0.92 | HSD11B1 (0.38) | FFAR4HSD11B1HRH3 | |
| SCHEMBL2701197 | 0.92 | HSD11B1 (0.38) | FFAR4HSD11B1HRH3 | |
| SCHEMBL550413 | 0.92 | HSD11B1 (0.38) | FFAR4HSD11B1HRH3 | |
| SCHEMBL2701199 | 0.92 | HSD11B1 (0.38) | FFAR4HSD11B1HRH3 | |
| SCHEMBL549770 | 0.92 | HSD11B1 (0.38) | FFAR4HSD11B1HRH3 | |
| SCHEMBL550412 | 0.92 | HSD11B1 (0.38) | FFAR4HSD11B1HRH3 | |
| SCHEMBL550700 | 0.85 | FFAR4 (0.45) | FFAR4HSD11B1 | |
| SCHEMBL2698314 | 0.85 | FFAR4 (0.45) | FFAR4HSD11B1 | |
| SCHEMBL550699 | 0.85 | FFAR4 (0.45) | FFAR4HSD11B1 | |
| SCHEMBL551029 | 0.85 | FFAR4 (0.45) | FFAR4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122858-A1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122858-A1 | LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | HSD11B1, HSD11B2, HSD17B1 | FFAR4 3238/4885HSD11B1 1/4885AADAT 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.