Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271646 | 0.75 | CDK1 (0.56) | PNPMAPTCDK1CDK4CDK2 | |
| Hydrochloric Acid SCHEMBL12474436 | 0.73 | CDK1 (0.54) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL12284639 | 0.71 | ALDH1A1 (0.65) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL13022826 | 0.71 | PNP (0.46) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL18519931 | 0.68 | MAPT (0.44) | PNPMAPTCDK1CDK4CDK2 | |
| Sulfuric Acid SCHEMBL21495047 | 0.67 | CDK1 (0.47) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL12820655 | 0.67 | CDK1 (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL11681028 | 0.67 | MAPT (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL31727983 | 0.67 | PNP (0.42) | PNPMAPTCDK1CDK4CDK2 | |
| SCHEMBL11678082 | 0.67 | PNP (0.42) | PNPMAPTCDK1CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9993491-B2 | Guanine riboswitch binding compounds and their use as antibiotics | SOCPRA—SCIENCES ET GÉNIE S.E.C. (CA) | 2018-06-12 | — | — | US | disclosed |
| US-9993491-B2 | Guanine riboswitch binding compounds and their use as antibiotics | SOCPRA—SCIENCES ET GÉNIE S.E.C. (CA) | 2018-06-12 | — | — | US | disclosed |
| EP-2440533-B1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA SCIENCES ET GÉNIE S E C (CA) | 2015-09-23 | — | — | EP | disclosed |
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | UNIVERSITE DE SHERBROOKE (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | UNIVERSITE DE SHERBROOKE (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA - SCIENCES ET GENIE S.E.C. (CA) | 2012-05-17 | — | — | US | disclosed |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | SOCPRA - SCIENCES ET GENIE S.E.C. (CA) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150890-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | GDA, RNMT, GNPDA1 | PNP 618/4885MAPT 4810/4885CDK1 4138/4885 |
| US-20120122819-A1 | GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS | GDA, RNMT, GNPDA1 | PNP 618/4885MAPT 4810/4885CDK1 4138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.