Ethylene Glycol

Ethylene Glycol

SCHEMBL4570276

C=C(c1ccccc1)C(CCC)CCCCC.OCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.39
CTSG P08311 2/20 0.39
CTRB1 P17538 2/20 0.39
CMA1 P23946 2/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP12 P39900 1/20 0.39
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
CSNK1E P49674 1/20 0.37
PTGS2 P35354 1/20 0.37
HDAC8 Q9BY41 4/20 0.36
HDAC3 O15379 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NAAA Q02083 1/20 0.36
CNR2 P34972 1/20 0.36
NR5A2 O00482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200443 0.80 CES2 (0.42) PRSS1CTSGCTRB1CMA1CES2
SCHEMBL5034590 0.80 SMN1; SMN2 (0.39) CES2CES1PTGS2HDAC8HDAC3
SCHEMBL28770741 0.76 MMP2 (0.58) PRSS1CTSGCTRB1CMA1MMP2
SCHEMBL5036785 0.75 PTGS2 (0.42) PRSS1CTSGCTRB1CMA1CES2
SCHEMBL18754825 0.73 HDAC3 (0.33) PRSS1CTSGCTRB1CMA1HDAC8
SCHEMBL16906433 0.72 MMP2 (0.40) PRSS1CTSGCTRB1CMA1MMP2
SCHEMBL4570275 0.72 PRSS1 (0.38) PRSS1CTSGCTRB1CMA1MMP2
SCHEMBL11215655 0.72 SMN1; SMN2 (0.47) MMP2MMP9MMP12CES2CES1
SCHEMBL9576675 0.71 MMP2 (0.61) PRSS1CTSGCTRB1CMA1MMP2
SCHEMBL14021741 0.71 SLC7A5 (0.37) PRSS1CTSGCTRB1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569509-B2 Method for producing catalyst for fuel cell NISSAN MOTOR CO., LTD. (JP) 2009-08-04 US disclosed
US-20070231620-A1 Platinum/iridium alloy; forming inverted micelle consisting of aqueous solution containing iridium compound clathrated by surfactant, by mixing organic solvent containing surfactant NISSAN MOTOR CO., LTD. (JP) 2007-10-04 US disclosed