Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.79 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | TFEB | P19484 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056670 | 1.00 | NFE2L2 (0.79) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| SCHEMBL6776487 | 1.00 | NFE2L2 (0.79) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| 2,6-Dimethoxybenzoic Acid SCHEMBL8133347 | 0.93 | NFE2L2 (0.68) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| 2,6-Dimethoxybenzoic Acid SCHEMBL8133343 | 0.93 | NFE2L2 (0.68) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| SCHEMBL2744353 | 0.88 | NFE2L2 (1.00) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| SCHEMBL2744350 | 0.88 | NFE2L2 (1.00) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| SCHEMBL6844087 | 0.87 | NFE2L2 (0.74) | NFE2L2TRPM8CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL6844089 | 0.87 | NFE2L2 (0.74) | NFE2L2TRPM8CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL14950768 | 0.87 | NFE2L2 (0.79) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 | |
| SCHEMBL14691500 | 0.86 | NFE2L2 (0.60) | NFE2L2TRPM8KDM4ECYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-113024573-A | Epodophyllotoxin derivative, preparation method and application thereof in preparation of antitumor drugs | 江苏百奥信康医药科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| EP-3307395-B1 | SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS | ISP INVESTMENTS LLC (US) | 2020-08-05 | — | — | EP | claimed |
| EP-3600224-A1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP Investments LLC (US) | 2020-02-05 | — | — | EP | claimed |
| WO-2018175836-A1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2018-09-27 | — | — | WO | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| CN-108181388-A | A kind of method for differentiating willow type propolis and yang gum | 中国农业科学院蜜蜂研究所 | 2018-06-19 | — | — | CN | claimed |
| EP-3310444-A1 | WATER-IN-OIL SUNSCREEN COMPOSITION HAVING ORGANIC SUNSCREEN ACTIVES | L'Oréal (FR) | 2018-04-25 | — | — | EP | claimed |
| WO-2016204946-A1 | WATER-IN-OIL SUNSCREEN COMPOSITION HAVING ORGANIC SUNSCREEN ACTIVES | L'OREAL (FR) | 2016-12-22 | — | — | WO | claimed |
| WO-2006108553-A1 | METHOD OF MOLLUSC CONTROL | SYNGENTA PARTICIPATIONS AG. (CH) | 2006-10-19 | — | — | WO | claimed |
| US-7033424-B2 | Phase change inks | XEROX CORPORATION (US) | 2006-04-25 | — | — | US | claimed |
| US-20060021546-A1 | Processes for preparing phase change inks | XEROX CORPORATION | 2006-02-02 | — | — | US | claimed |
| US-20060020141-A1 | Metallized dye | XEROX CORPORATION | 2006-01-26 | — | — | US | claimed |
| US-20060016369-A1 | PHASE CHANGE INKS | XEROX CORPORATION | 2006-01-26 | — | — | US | claimed |
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | claimed |
| US-6946025-B2 | Process for preparing tetra-amide compounds | XEROX CORPORATION (US) | 2005-09-20 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| US-6451334-B2 | PULSE ADMINISTERING OF A C1-C4 SUBSTITUTED AND/OR PHENYL SUBSTITUTED CARBOXYLIC ACID AND SALTS AND A CARRIER OR DILUENT TO STIMULATE CELLS IN TREATING BLOOD DISORDERS, E.G. SICKLE CELL ANEMIA, THALASSEMIA, BLOOD LOSS ETC. | Perrine, Susan P. | 2002-09-17 | — | — | US | claimed |
| WO-2002015691-A1 | USE FOR CONIFER SAPLING PROTECTION AGAINST INSECT ATTACK | ROBIGUS AB (SE) | 2002-02-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | NFE2L2 4821/4885TRPM8 4585/4885KDM4E 2134/4885 |
| US-20060020141-A1 | Metallized dye | CDYL, CDY1; CDY1B, CDYL2 | NFE2L2 1266/4885TRPM8 2210/4885KDM4E 1814/4885 |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | NFE2L2 3435/4885TRPM8 3148/4885KDM4E 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.