Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837841 | 0.82 | MGAM (0.40) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL284647 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL13555039 | 0.78 | CPA1 (0.44) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL13541257 | 0.78 | CPA1 (0.44) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL17617124 | 0.78 | CPA1 (0.44) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL131332 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL21981164 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL28904001 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL29207090 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL4957929 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1NPC1KMT2ACPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120123119-A1 | ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123119-A1 | ACYCLIC NUCLEOSIDE DERIVATIVES | NUDT1, PNP, NSUN2 | ALDH1A1 2200/4885MEN1 1895/4885NPC1 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.