Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570452 | 0.82 | ALDH1A1 (0.37) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8719366 | 0.82 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1246334 | 0.81 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL204730 | 0.80 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27555145 | 0.79 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9203447 | 0.78 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6868422 | 0.78 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27941511 | 0.78 | ALDH1A1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28133875 | 0.78 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9055012 | 0.76 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801644-A4 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE POULENC RORER PHARMA (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0801644-A1 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5556990-A | SQUALENE SYNTHASE INHIBITORS, ANTICHOLESTEROL AGENTS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1996018615-A1 | POLYARYLCARBAMOYLAZA -AND- CARBAMOYLALKANEDIOIC ACIDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-06-20 | — | — | WO | disclosed |