Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 8/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751436 | 0.77 | — | — | |
| SCHEMBL30803768 | 0.77 | — | — | |
| SCHEMBL12724708 | 0.77 | AURKA (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL14606030 | 0.76 | — | — | |
| SCHEMBL10138646 | 0.76 | — | — | |
| SCHEMBL18232212 | 0.74 | SORT1 (0.43) | SORT1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15357779 | 0.72 | FLT3 (0.41) | SORT1CYP1A2HRH4PIK3C3 | |
| SCHEMBL171800 | 0.72 | HRH4 (0.46) | SORT1HRH4PIK3C3GRM5 | |
| SCHEMBL396081 | 0.72 | MAPK8 (0.32) | — | |
| SCHEMBL28726329 | 0.71 | SORT1 (0.41) | SORT1HRH4PIK3C3GRM5GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481705-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160130295-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-05-12 | — | — | US | disclosed |
| US-9211520-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150329583-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | ENERGY, UNITED STATES DEPARTMENT OF | 2015-11-19 | — | — | US | disclosed |
| US-8951480-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-8765933-B2 | Asynthesis of β-nucleosides | PHARMAESSENTIA CORP. (TW) | 2014-07-01 | — | — | US | disclosed |
| US-20120259106-A1 | ASYNTHESIS OF B-NUCLEOSIDES | PHARMAESSENTIA CORP. (TW) | 2012-10-11 | — | — | US | disclosed |
| US-20120107175-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130295-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | RAD18, MVD, USP18 | SORT1 4798/4885CYP1A2 2367/4885CYP3A4 1739/4885 |
| US-20120259106-A1 | ASYNTHESIS OF B-NUCLEOSIDES | ATIC, DPYD, DUT | SORT1 3660/4885CYP1A2 552/4885CYP3A4 1115/4885 |
| US-20150329583-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | RAD18, MVD, USP18 | SORT1 4798/4885CYP1A2 2367/4885CYP3A4 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.