SCHEMBL4570689

SCHEMBL4570689

C/C=C/c1ccc(/C=C/OC=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
LMNA P02545 2/20 0.48
CYP3A4 P08684 2/20 0.48
KDM4E B2RXH2 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
CNR2 P34972 1/20 0.36
TYR P14679 1/20 0.36
MAPT P10636 3/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.33
POLB P06746 1/20 0.33
CYP2A6 P11509 2/20 0.31
F3 P13726 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10299701 0.78 CYP2C19 (0.39) ALDH1A1LMNACYP3A4KDM4EMAPT
SCHEMBL2770699 0.78 KDM4E (0.54) ALDH1A1LMNACYP3A4KDM4ETP53
SCHEMBL14394762 0.78 TRPA1 (0.47) ALDH1A1LMNAMAPTSMN1; SMN2CYP2A6
SCHEMBL9702187 0.78 CYP1A2 (0.52) ALDH1A1LMNAKDM4ETP53TSHR
SCHEMBL173274 0.77 ALDH1A1 (0.50) ALDH1A1LMNAMAPTSMN1; SMN2CYP2A6
SCHEMBL12298544 0.77 ALDH1A1 (0.50) ALDH1A1LMNAMAPTSMN1; SMN2CYP2A6
Ammonia Solution, Strong SCHEMBL17394609 0.76 ALDH1A1 (0.48) ALDH1A1LMNAMAPTSMN1; SMN2CYP2A6
SCHEMBL9461723 0.75 CYP3A4 (0.65) ALDH1A1LMNACYP3A4KDM4ETP53
SCHEMBL333123 0.75 CYP3A4 (0.65) ALDH1A1LMNACYP3A4KDM4ETP53
SCHEMBL7527708 0.75 CYP3A4 (0.65) ALDH1A1LMNACYP3A4KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940392-B2 Titanium based inorganic-organic hybrid solid material, method for preparing same and uses thereof UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2015-01-27 US disclosed
US-20120121904-A1 TITANIUM BASED INORGANIC-ORGANIC HYBRID SOLID MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF L'UNIVERSITE PIERRE ET MARIE CURIE, (PARIS 6) (FR) 2012-05-17 US disclosed