Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC33A1 | O00400 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892470 | 0.92 | SLC33A1 (0.37) | SLC33A1SCN9APDE9A | |
| SCHEMBL1890290 | 0.86 | SLC33A1 (0.36) | SLC33A1SCN9APDE9A | |
| SCHEMBL1891885 | 0.80 | SLC33A1 (0.52) | SLC33A1 | |
| SCHEMBL27771379 | 0.77 | CYP19A1 (0.40) | — | |
| SCHEMBL2843744 | 0.76 | GRM1 (0.36) | — | |
| SCHEMBL1891557 | 0.76 | AGTR1 (0.38) | — | |
| SCHEMBL27792572 | 0.76 | HIF1A (0.38) | HRH3ALDH1A1 | |
| SCHEMBL1891360 | 0.76 | HRH3 (0.43) | SLC33A1HRH3 | |
| SCHEMBL27771360 | 0.76 | ALOX12 (0.41) | KDM4E | |
| SCHEMBL4447793 | 0.76 | PPARA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |