Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447793 | 0.92 | PPARA (0.37) | XDH | |
| SCHEMBL1890807 | 0.91 | AGTR1 (0.39) | F10AGTR1 | |
| SCHEMBL2869467 | 0.86 | APLNR (0.39) | — | |
| SCHEMBL27792572 | 0.84 | HIF1A (0.38) | CYP19A1 | |
| SCHEMBL2842327 | 0.84 | PPARG (0.40) | AGTR1 | |
| SCHEMBL27771379 | 0.84 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL1893800 | 0.84 | SLC33A1 (0.40) | F10AGTR1 | |
| SCHEMBL1892167 | 0.83 | AGTR1 (0.40) | F10AGTR1 | |
| SCHEMBL27792668 | 0.83 | LMNA (0.41) | CYP19A1 | |
| SCHEMBL4167260 | 0.83 | FFAR1 (0.39) | F10AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256115-A1 | Heteromonocyclic compound and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2010-12-01 | — | — | EP | disclosed |