SCHEMBL4570865

SCHEMBL4570865

CCNC(=S)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80644 0.83
SCHEMBL14192214 0.78 KDM4E (0.45)
SCHEMBL9527845 0.77
SCHEMBL5455098 0.77
SCHEMBL8221848 0.75 ALDH1A1 (0.46)
SCHEMBL8209943 0.75 ALDH1A1 (0.46)
Noxytiolin SCHEMBL171505 0.75
SCHEMBL20615036 0.75 ALDH1A1 (0.46)
SCHEMBL13368352 0.73
SCHEMBL16709986 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4627968-A Synthesis of crystalline aluminosilicate with alkylurea or alkylthiourea ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-12-09 US claimed
EP-3188764-B1 POLYMER AND CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING INCLUDING THE POLYMER CANON KK (JP) 2023-08-23 EP disclosed
WO-2023011416-A1 MULTI-TARGET INHIBITOR TARGETING HDAC AND NAD SYNTHESIS AND USE OF MULTI-TARGET INHIBITOR 中国海洋大学 2023-02-09 WO disclosed
CN-114106475-A Rubber composition for sealing material, and pneumatic tire 住友橡胶工业株式会社 2022-03-01 CN disclosed
US-10947206-B2 cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2021-03-16 US disclosed
US-20190160172-A1 BONE FRACTURE REPAIR BY TARGETING OF AGENTS THAT PROMOTE BONE HEALING PURDUE RESEARCH FOUNDATION (US) 2019-05-30 US disclosed
US-20170296566-A9 METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS GLYCOMIMETICS, INC. (US) 2017-10-19 US disclosed
US-9630910-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-04-25 US disclosed
US-20160263250-A1 Imaging Beta Cell Mass THE GENERAL HOSPITAL CORPORATION 2016-09-15 US disclosed
US-20160243145-A1 METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS GLYCOMIMETICS, INC. (US) 2016-08-25 US disclosed
EP-0162475-B1 PROCESS FOR PRODUCING CYCLIC ALCOHOL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-08-21 EP disclosed
US-4661639-A CATALYTIC HYDRATION OF CYCLIC OLEFINS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1987-04-28 US disclosed
US-4649138-A S-(AMINOALKYL) ISOTHIOUREA AS IMMUNOSUPPRESSANT SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) 1987-03-10 US disclosed
US-4627968-A Synthesis of crystalline aluminosilicate with alkylurea or alkylthiourea ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-12-09 US disclosed
EP-0162475-A2 Process for producing cyclic alcohol Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-11-27 EP disclosed
US-4490387-A ISOTHIOUREA DERIVATIVES WHICH HAVE IMMONOSUPPRESSANT ACTIVITY SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1984-12-25 US disclosed
US-4447337-A WITH MOLYBDENUM COMPOUND AND A THIOUREA MONSANTO COMPANY (US) 1984-05-08 US disclosed
US-4378365-A IMMUNOSUPPRESSANT, ANTIARTHRITIC, ANTIINFLAMMATORY; S-(AMINOALKYL)-ISOTHIOUREAS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1983-03-29 US disclosed
US-4294854-A S-(AMINOALKYL) ISOTHIOUREAS WHICH HAVE IMMUNOSUPPRESANT ACTIVITY, IN TREATING RHEUMATOID ARTHRITIS, PSORIASIS, REDUCING INFLAMMATION SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-10-13 US disclosed
US-4205071-A Pharmaceutical compositions having immunosuppressant activity and methods therefor SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-05-27 US disclosed