Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31753526 | 0.85 | POLB (0.46) | ALDH1A1NPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL8221437 | 0.85 | POLB (0.46) | ALDH1A1NPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL15841353 | 0.83 | POLB (0.44) | ALDH1A1NPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL13856955 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CYP3A4NPSR1LMNASMN1; SMN2 | |
| SCHEMBL8221848 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP3A4NPSR1LMNAGAA | |
| SCHEMBL21761727 | 0.76 | LMNA (0.36) | ALDH1A1NPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL4570865 | 0.75 | — | — | |
| SCHEMBL21761728 | 0.73 | POLB (0.39) | ALDH1A1NPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL8217967 | 0.73 | KMT2A (0.51) | ALDH1A1NPSR1LMNASMN1; SMN2HTT | |
| SCHEMBL8209950 | 0.73 | MAPT (0.56) | ALDH1A1CYP3A4LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123350-B2 | Metal delivery agents and therapeutic uses of the same | THE UNIVERSITY OF MELBOURNE (AU) | 2021-09-21 | — | — | US | disclosed |
| US-20190298734-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2019-10-03 | — | — | US | disclosed |
| US-10413554-B2 | Metal delivery agents and therapeutic uses of the same | UNIV MELBOURNE (AU) | 2019-09-17 | — | — | US | disclosed |
| US-20180140613-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2018-05-24 | — | — | US | disclosed |
| US-20180140613-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2018-05-24 | — | — | US | disclosed |
| EP-3238719-A1 | METAL DELIVERY AGENTS FOR THE TREATMENT OF MULTIPLE SCLEROSIS | The University of Melbourne (AU) | 2017-11-01 | — | — | EP | disclosed |
| EP-2813223-B1 | Metal delivery agents and terapeutic uses of the same | UNIV MELBOURNE (AU) | 2017-10-25 | — | — | EP | disclosed |
| US-20150105461-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2015-04-16 | — | — | US | disclosed |
| US-20150105461-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | THE UNIVERSITY OF MELBOURNE (AU) | 2015-04-16 | — | — | US | disclosed |
| EP-2813223-A1 | Metal delivery agents and terapeutic uses of the same | The University of Melbourne (AU) | 2014-12-17 | — | — | EP | disclosed |
| US-20120270850-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | UNIVERSITY OF MEDLBOURNE (AU) | 2012-10-25 | — | — | US | disclosed |
| US-20120270850-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | UNIVERSITY OF MEDLBOURNE (AU) | 2012-10-25 | — | — | US | disclosed |
| WO-2008061306-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | THE UNIVERSITY OF MELBOURNE (AU) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270850-A1 | METAL DELIVERY AGENTS AND THERAPEUTIC USES OF THE SAME | SOD1, SLC30A6, SLC30A5 | ALDH1A1 1523/4885CYP3A4 4635/4885NPSR1 2215/4885 |
| US-10413554-B2 | Metal delivery agents and therapeutic uses of the same | SOD1, SLC30A6, SLC30A5 | ALDH1A1 1497/4885CYP3A4 4683/4885NPSR1 2231/4885 |
| US-20150105461-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | SOD1, SLC30A6, SLC30A5 | ALDH1A1 1523/4885CYP3A4 4635/4885NPSR1 2215/4885 |
| US-20180140613-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | SOD1, SLC30A6, SLC30A5 | ALDH1A1 1523/4885CYP3A4 4635/4885NPSR1 2215/4885 |
| US-11123350-B2 | Metal delivery agents and therapeutic uses of the same | SOD1, SLC30A6, SLC30A5 | ALDH1A1 1523/4885CYP3A4 4635/4885NPSR1 2215/4885 |
| US-20190298734-A1 | Metal Delivery Agents and Therapeutic Uses of the Same | SOD1, SLC30A6, SLC30A5 | ALDH1A1 1523/4885CYP3A4 4635/4885NPSR1 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.