SCHEMBL45720

SCHEMBL45720

CCNC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
KMT2A Q03164 2/20 0.54
GAA P10253 1/20 0.54
HSD17B10 Q99714 1/20 0.54
PARP1 P09874 6/20 0.52
MAPK14 Q16539 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
FURIN P09958 1/20 0.47
MAP3K7 O43318 1/20 0.47
CDK8 P49336 1/20 0.47
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13702256 0.92 CDK8 (0.56) SMN1; SMN2PARP1L3MBTL1CDK8ALDH1A1
SCHEMBL23080259 0.91 HDAC6 (0.56) SMN1; SMN2KMT2AGAAHSD17B10MEN1
SCHEMBL9713054 0.91 SMN1; SMN2 (0.67) SMN1; SMN2KMT2AGAAHSD17B10PARP1
SCHEMBL2964483 0.86 L3MBTL1 (0.69) SMN1; SMN2KMT2AGAAHSD17B10PARP1
SCHEMBL13702344 0.84 AOC3 (0.54) SMN1; SMN2CDK8ALDH1A1
SCHEMBL10923209 0.84 KMT2A (0.51) SMN1; SMN2KMT2AGAAHSD17B10PARP1
SCHEMBL13702421 0.84 SMN1; SMN2 (0.59) SMN1; SMN2KMT2AGAAHSD17B10L3MBTL1
SCHEMBL13753330 0.84 SMN1; SMN2 (0.59) SMN1; SMN2KMT2AGAAHSD17B10L3MBTL1
SCHEMBL2972657 0.83 SMN1; SMN2 (0.84) SMN1; SMN2KMT2AGAAHSD17B10L3MBTL1
SCHEMBL5370898 0.82 SMN1; SMN2 (0.77) SMN1; SMN2GAAL3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240024-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING THE SAME, AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2024-07-18 US disclosed
US-20220380297-A1 COMPOUND, CORE-SHELL DYE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, AND COLOR FILTER SAMSUNG SDI CO LTD (KR) 2022-12-01 US disclosed
EP-2964654-A1 THIENO[3,2-D]PYRIMIDINE-6-CARBOXAMIDES AND ANALOGUES AS SIRTUIN MODULATORS Glaxosmithkline LLC (US) 2016-01-13 EP disclosed
WO-2014138562-A1 THIENO[3,2-D]PYRIMIDINE-6-CARBOXAMIDES AND ANALOGUES AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC (US) 2014-09-12 WO disclosed
EP-2591354-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT Ardelyx, Inc. (US) 2013-05-15 EP disclosed
WO-2012006475-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2012-01-12 WO disclosed
EP-1320531-A2 BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Pharmacia Italia S.p.A. (IT) 2003-06-25 EP disclosed
WO-2002012242-A2 BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PHARMACIA ITALIA S.P.A. (IT) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220380297-A1 COMPOUND, CORE-SHELL DYE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, AND COLOR FILTER SUN2, PSMD9, PSMD7 SMN1; SMN2 4619/4885KMT2A 566/4885GAA 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.