PSMD9

26S proteasome non-ATPase regulatory subunit 9 · O00233 · PSMD9 on Sugi Atlas →

21 patent compounds predicted against PSMD9, 17 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL21943538 SCHEMBL21943538 0.59 1/20
SCHEMBL21943762 SCHEMBL21943762 0.57 1/20
SCHEMBL21944043 SCHEMBL21944043 0.55 1/20
SCHEMBL21943004 SCHEMBL21943004 0.55 1/20
SCHEMBL21942995 SCHEMBL21942995 0.53 1/20
SCHEMBL21943411 SCHEMBL21943411 0.53 1/20
SCHEMBL14042267 SCHEMBL14042267 0.52 1/20
SCHEMBL21943429 SCHEMBL21943429 0.52 1/20
SCHEMBL22066328 SCHEMBL22066328 0.51 1/20
SCHEMBL21943540 SCHEMBL21943540 0.49 1/20
SCHEMBL21943537 SCHEMBL21943537 0.45 1/20
SCHEMBL24016281 SCHEMBL24016281 0.44 1/20
SCHEMBL24532074 SCHEMBL24532074 0.42 1/20
SCHEMBL1454562 SCHEMBL1454562 0.42 1/20
SCHEMBL17612956 SCHEMBL17612956 0.42 1/20
SCHEMBL12399198 SCHEMBL12399198 0.42 1/20
SCHEMBL29911712 SCHEMBL29911712 0.40 1/20

Clinical trials — most relevant to PSMD9 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease PHASE4UNKNOWN
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients PHASE4NOT_YET_RECRUITING
Doxorubicin and Bortezomib in Treating Patients With Liver Cancer PHASE2COMPLETED
Bortezomib in Treating Patients With Mantle Cell Lymphoma PHASE2COMPLETED
MLN9708 and Dexamethasone for High-Risk Smoldering Multiple Myeloma PHASE2WITHDRAWN
A Dose Escalation Study of Carfilzomib Taken With Thalidomide and Dexamethasone in Relapsed AL Amyloidosis PHASE1/PHASE2COMPLETED
Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors PHASE2COMPLETED
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
Study of Irinotecan and Bortezomib in Children With Recurrent/Refractory Neuroblastoma PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma PHASE1COMPLETED
Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer PHASE1COMPLETED
GO-203-2C + Bortezomib For Relapsed Or Refractory MM PHASE1WITHDRAWN
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS nanCOMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Effect of Diaphragm Stimulation During Surgery nanCOMPLETED
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Collection of Blood Samples for DNA in Motor Neuron Disease nanCOMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS) nanUNKNOWN
Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment nanUNKNOWN
Cardiovascular Complications of Carfilzomib Treatment nanUNKNOWN
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a PSMD9 binder may also engage these)

ProteinNameSimilarity
Q3SZ19 1.000 Q3SZ19 →
Q9CR00 1.000 Q9CR00 →
Q9WTV5 1.000 Q9WTV5 →
F4HQD4 0.978 F4HQD4 →
Q804S5 0.976 Q804S5 →
Q99MP8 0.975 Q99MP8 →
B4F7E7 0.974 B4F7E7 →
Q9SRU7 0.974 Q9SRU7 →
Q6GNY1 0.974 Q6GNY1 →
Q803R5 0.973 Q803R5 →
Q921X6 0.973 Q921X6 →
Q9S7C0 0.973 Q9S7C0 →
Q80SY4 0.973 Q80SY4 →
O93257 0.972 O93257 →
Q2USD7 0.972 Q2USD7 →
Q86YT6 0.972 Q86YT6 →
Q8K339 0.972 Q8K339 →
P93648 0.972 P93648 →
A2YQ56 0.972 A2YQ56 →
Q9Y6D5 0.972 Q9Y6D5 →
BRAP BRCA1-associated protein 0.972 landscape →
Q9VD25 0.971 Q9VD25 →
P54358 0.971 P54358 →
Q6WRS2 0.971 Q6WRS2 →
P51660 0.971 P51660 →
Q8TF65 0.971 Q8TF65 →
Q9UJA3 0.971 Q9UJA3 →
Q9ZVW2 0.971 Q9ZVW2 →
Q9CZU3 0.971 Q9CZU3 →
Q9VFS8 0.971 Q9VFS8 →