Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24632197 | 0.72 | ALOX5 (0.43) | — | |
| SCHEMBL30753545 | 0.67 | ST6GAL1 (0.66) | — | |
| SCHEMBL16378069 | 0.67 | HPGD (0.36) | HPGD | |
| SCHEMBL28111518 | 0.65 | DPP4 (0.35) | KDM4EGABRA1DPP4 | |
| SCHEMBL12599523 | 0.64 | HPGD (0.38) | HPGDALDH1A1KDM4ELMNAHSP90AA1 | |
| SCHEMBL13520169 | 0.63 | HPGD (0.43) | HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL30962312 | 0.62 | HPGD (0.35) | HPGDALDH1A1KDM4ELMNAHSP90AA1 | |
| SCHEMBL26579405 | 0.61 | L3MBTL1 (0.41) | ALDH1A1LMNAESR2 | |
| SCHEMBL29370739 | 0.61 | PARP1 (0.46) | HPGDALDH1A1KDM4EGABRA1SMN1; SMN2 | |
| SCHEMBL17141584 | 0.60 | DPP4 (0.33) | KDM4EDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452679-A1 | CYTOPROTECTIVE AGENT | National University Corporation Tokyo University Of Agriculture and Technology (JP) | 2012-05-16 | — | — | EP | disclosed |