Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519615 | 0.77 | ADRB2 (0.35) | MAOAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL14490157 | 0.74 | DRD2 (0.41) | HPGDMAOADRD2DRD3MAOB | |
| SCHEMBL7079080 | 0.74 | MAOA (0.46) | MAOADRD2MAOB | |
| SCHEMBL13443211 | 0.73 | HPGD (0.40) | HPGDMAOACA1CA9MAOB | |
| SCHEMBL12599523 | 0.72 | HPGD (0.38) | HPGDCA1CA9KDM4EALDH1A1 | |
| SCHEMBL1285699 | 0.70 | MAOA (0.51) | HPGDMAOADRD2MAOBKDM4E | |
| SCHEMBL30962312 | 0.70 | HPGD (0.35) | HPGDMAOACA1CA9MAOB | |
| SCHEMBL13443205 | 0.69 | HPGD (0.35) | HPGDCA1CA9KDM4E | |
| SCHEMBL31314432 | 0.68 | ALOX5 (0.41) | HPGDCA1CA9LMNACASP1 | |
| SCHEMBL1567962 | 0.68 | ALOX5 (0.41) | HPGDCA1CA9LMNACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | disclosed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | TFB2M, TFAM, SHMT2 | HPGD 304/4885MAOA 840/4885CA1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.