SCHEMBL457237

SCHEMBL457237

Cc1cccc(OB(Oc2cccc(C)c2C)Oc2cccc(C)c2C)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
HTR1B P28222 1/20 0.46
TRPA1 O75762 1/20 0.41
ATM Q13315 1/20 0.41
KEAP1 Q14145 1/20 0.41
POLB P06746 1/20 0.41
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CYP2C19 P33261 2/20 0.38
DHFR P00374 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.37
CYP2A6 P11509 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29703714 1.00 MAPT (0.48) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL30338488 0.84 MAPT (0.47) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL457239 0.84 MAPT (0.47) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL3889703 0.82 MAPT (0.46) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL29435906 0.80 TSHR (0.46) KDM4EMEN1KMT2ACYP1A2CYP2C19
SCHEMBL717122 0.80 TSHR (0.46) KDM4EMEN1KMT2ACYP1A2CYP2C19
SCHEMBL6035270 0.77 MAPT (0.54) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL1538371 0.77 MAPT (0.54) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL29377898 0.77 MAPT (0.54) MAPTHTR1BTRPA1ATMKEAP1
SCHEMBL3900215 0.76 MAPT (0.44) MAPTHTR1BTRPA1ATMKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157794-A Cycloolefin copolymer and preparation method thereof 万华化学集团股份有限公司 2025-06-17 CN claimed
CN-120059436-A High-transparency scratch-resistant polycarbonate material 厦门天宇新材料科技有限公司 2025-05-30 CN claimed
CN-119708316-A Ethylene/alpha-olefin gradient copolymer and preparation method thereof 中国科学院长春应用化学研究所 2025-03-28 CN claimed
CN-118994450-A Process for preparing ultra-high molecular weight narrow distribution poly alpha-olefin 陕西煤业化工技术研究院有限责任公司 2024-11-22 CN claimed
CN-118894891-A Thioether-functionalized rare earth complex with limited geometric configuration, preparation method thereof, multipolymer and preparation method thereof 中国科学院长春应用化学研究所 2024-11-05 CN claimed
CN-115197355-B Ethylene/butadiene copolymer with high breakdown voltage and preparation method thereof 中国科学院长春应用化学研究所 2023-11-07 CN claimed
CN-115260367-B Use of rare earth metal complexes in the preparation of ethylene/butadiene copolymers from ethylene and 1, 3-butadiene 中国科学院长春应用化学研究所 2023-10-10 CN claimed
CN-113480690-B Multipolymer and preparation method thereof 中国科学院长春应用化学研究所 2023-05-05 CN claimed
CN-101052660-B Polymerization catalyst for conjugated diene polymer, process for producing conjugated diene polymer using the same, rubber composition for tire, and rubber composition for golf ball UBE INDUSTRIES 2010-07-14 CN claimed
CN-120157794-A Cycloolefin copolymer and preparation method thereof 万华化学集团股份有限公司 2025-06-17 CN disclosed
CN-120059436-A High-transparency scratch-resistant polycarbonate material 厦门天宇新材料科技有限公司 2025-05-30 CN disclosed
CN-119708316-A Ethylene/alpha-olefin gradient copolymer and preparation method thereof 中国科学院长春应用化学研究所 2025-03-28 CN disclosed
CN-119119337-A Preparation method of liquid rubber, liquid rubber and rubber composite material 中国科学院长春应用化学研究所 2024-12-13 CN disclosed
CN-118994450-A Process for preparing ultra-high molecular weight narrow distribution poly alpha-olefin 陕西煤业化工技术研究院有限责任公司 2024-11-22 CN disclosed
CN-101443343-A Metallocene complex and polymerization catalyst composition containing the same RIKEN (JP) 2009-05-27 CN disclosed
CN-101400707-A Polymerization catalyst composition for polymerization of isoprene compound RIKEN (JP) 2009-04-01 CN disclosed
CN-101052660-A Polymerization catalyst for conjugated diene polymer, process for producing conjugated diene polymer using the same, rubber composition for tire, and rubber composition for golf ball UBE INDUSTRIES (JP) 2007-10-10 CN disclosed
CN-101010349-A Polymerization catalyst composition containing metallocene complex and polymer prepared using the same RIKEN (JP) 2007-08-01 CN disclosed
US-20010007009-A1 Transition metal catalyzed polymerization of olefinic monomers in a water-containing polymerization medium BASF AKTIENGESELLSCHAFT (DE) 2001-07-05 US disclosed
EP-0656373-B1 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI CHEMICALS INC (JP) 1998-07-29 EP disclosed