SCHEMBL457239

SCHEMBL457239

Cc1cccc(OB(O)O)c1C

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
TRPA1 O75762 1/20 0.44
ATM Q13315 1/20 0.44
HTR1B P28222 1/20 0.44
POLB P06746 1/20 0.43
KEAP1 Q14145 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
DHFR P00374 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30338488 1.00 MAPT (0.47) MAPTTRPA1ATMHTR1BPOLB
SCHEMBL3889703 0.89 MAPT (0.46) MAPTTRPA1ATMHTR1BPOLB
SCHEMBL457237 0.84 MAPT (0.48) MAPTTRPA1ATMHTR1BPOLB
SCHEMBL29703714 0.84 MAPT (0.48) MAPTTRPA1ATMHTR1BPOLB
SCHEMBL27764640 0.83 TRPA1 (0.52) MAPTTRPA1ATMPOLBLMNA
SCHEMBL3900215 0.82 MAPT (0.44) MAPTTRPA1ATMHTR1BPOLB
SCHEMBL31629381 0.82 TRPA1 (0.34) MAPTTRPA1ATM
SCHEMBL5892479 0.82 TRPA1 (0.34) MAPTTRPA1ATM
SCHEMBL30366069 0.81 TSHR (0.45) LMNARAB9AALDH1A1MEN1KMT2A
SCHEMBL350128 0.81 TSHR (0.45) LMNARAB9AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157794-A Cycloolefin copolymer and preparation method thereof 万华化学集团股份有限公司 2025-06-17 CN claimed
CN-120059436-A High-transparency scratch-resistant polycarbonate material 厦门天宇新材料科技有限公司 2025-05-30 CN claimed
CN-119708316-A Ethylene/alpha-olefin gradient copolymer and preparation method thereof 中国科学院长春应用化学研究所 2025-03-28 CN claimed
CN-118994450-A Process for preparing ultra-high molecular weight narrow distribution poly alpha-olefin 陕西煤业化工技术研究院有限责任公司 2024-11-22 CN claimed
CN-118894891-A Thioether-functionalized rare earth complex with limited geometric configuration, preparation method thereof, multipolymer and preparation method thereof 中国科学院长春应用化学研究所 2024-11-05 CN claimed
CN-115197355-B Ethylene/butadiene copolymer with high breakdown voltage and preparation method thereof 中国科学院长春应用化学研究所 2023-11-07 CN claimed
CN-115260367-B Use of rare earth metal complexes in the preparation of ethylene/butadiene copolymers from ethylene and 1, 3-butadiene 中国科学院长春应用化学研究所 2023-10-10 CN claimed
CN-113480690-B Multipolymer and preparation method thereof 中国科学院长春应用化学研究所 2023-05-05 CN claimed
CN-112321628-B Preparation method of beta-dimethylphenyl silicon substituted organic nitrile compound 湖北工程学院 2023-04-28 CN claimed
CN-101400709-B Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL CO 2012-07-18 CN claimed
CN-101052660-B Polymerization catalyst for conjugated diene polymer, process for producing conjugated diene polymer using the same, rubber composition for tire, and rubber composition for golf ball UBE INDUSTRIES 2010-07-14 CN claimed
US-20260001976-A1 A PROPYLENE-ETHYLENE RANDOM COPOLYMER FOR PIPE APPLICATIONS BOREALIS AG (AT) 2026-01-01 US disclosed
CN-120157794-A Cycloolefin copolymer and preparation method thereof 万华化学集团股份有限公司 2025-06-17 CN disclosed
CN-120059436-A High-transparency scratch-resistant polycarbonate material 厦门天宇新材料科技有限公司 2025-05-30 CN disclosed
CN-119708316-A Ethylene/alpha-olefin gradient copolymer and preparation method thereof 中国科学院长春应用化学研究所 2025-03-28 CN disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1999005152-A1 METHOD FOR PRODUCING METALLOCENES TARGOR GMBH (DE) 1999-02-04 WO disclosed
EP-0656373-B1 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI CHEMICALS INC (JP) 1998-07-29 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001976-A1 A PROPYLENE-ETHYLENE RANDOM COPOLYMER FOR PIPE APPLICATIONS PEX3, MPC2, LBR MAPT 1421/4885TRPA1 1487/4885ATM 2025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.