SCHEMBL3889703

SCHEMBL3889703

Cc1cccc(OB(O)Oc2cccc(C)c2C)c1C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
HTR1B P28222 1/20 0.43
TRPA1 O75762 1/20 0.43
ATM Q13315 1/20 0.43
POLB P06746 1/20 0.42
KEAP1 Q14145 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
DHFR P00374 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30338488 0.89 MAPT (0.47) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL457239 0.89 MAPT (0.47) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL5858381 0.85 POLB (0.40) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL457237 0.82 MAPT (0.48) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL30197899 0.82 CA1 (0.44) LMNARAB9AALDH1A1MEN1KMT2A
SCHEMBL29703714 0.82 MAPT (0.48) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL3900215 0.80 MAPT (0.44) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL314705 0.75 MAPT (0.50) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL11788173 0.75 MAPT (0.50) MAPTHTR1BTRPA1ATMPOLB
SCHEMBL1538371 0.74 MAPT (0.54) MAPTHTR1BTRPA1ATMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed